DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and lsh1

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_592867.1	Gene:	lsh1 / 2541537	PomBaseID:	SPAC1F5.06	Length:	848	Species:	Schizosaccharomyces pombe

Alignment Length:	510	Identity:	110/510 - (21%)
Similarity:	196/510 - (38%)	Gaps:	105/510 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 WPRF-----GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMAN 61
            |..|     .|..|......|.::.....|::..|...|..|:.:.:.|...| .|:.|......
pombe    17 WHAFASSVLAIDYGTEWTKAALIKPGIPLEIVLTKDTRRKEQSAVAFKGNERI-FGVDASNLATR 80

  Fly    62 RPRQAVAHSFQLLQPKEELTEEKLSSAL-REIPCDFDKEELVFRMEHT-----VPSDREDQD-DR 119
            .|    |||.:  ..||.|....|.|.| ::....:...:||...|.|     |.||.|:.. :.
pombe    81 FP----AHSIR--NVKELLDTAGLESVLVQKYQSSYPAIQLVENEETTSGISFVISDEENYSLEE 139

  Fly   120 VVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQ 184
            ::...:..|....|      |:||:..||      .||::|.::......:|.:||:....||..
pombe   140 IIAMTMEHYISLAE------EMAHEKITD------LVLTVPPHFNELQRSILLEAARILNKHVLA 192

  Fly   185 IITEPTAAVLGYSIGEE-QTEQRRHVLTIKCGGLYSD--IAFYSVQNGLFVQ---------LATF 237
            :|.:..|..:.||:... .|:...:::.....|..|.  |:|.:|:.....:         ||:.
pombe   193 LIDDNVAVAIEYSLSRSFSTDPTYNIIYDSGSGSTSATVISFDTVEGSSLGKKQNITRIRALASG 257

  Fly   238 GPFPIGGRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLM 302
            ....:.|.:....|:.|:...|.:|:.:|...:.|::|::...|...||||:........|:.|.
pombe   258 FTLKLSGNEINRKLIGFMKNSFYQKHGIDLSHNHRALARLEKEALRVKHILSANSEAIASIEELA 322

  Fly   303 DGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAV 367
            ||:|:..:::|:..|||.:.:.:..::.:.:.:::|...   .|:|:.|:|.|...:||.:|:.:
pombe   323 DGIDFRLKITRSVLESLCKDMEDAAVEPINKALKKANLT---FSEINSIILFGGASRIPFIQSTL 384

  Fly   368 GARFPDAKLHNSHSADEVVAIGCARQAVCL-----IDPLEQQLHKEEDCVVAEDDLFIWHGNDES 427
            .......|:..:.:|||....|.|.....|     :.||           :.:|
pombe   385 ADYVSSDKISKNVNADEASVKGAAFYGASLTKSFRVKPL-----------IVQD----------- 427

  Fly   428 NAKLVLGRGSVLPAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDST 482
                            .|:.|                :.|..|.||.:..|||||
pombe   428 ----------------IINYP----------------YLLSLGTSEYIVALPDST 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	94/412 (23%)
lsh1	NP_592867.1	DnaK	19..667	CDD:223520	109/508 (21%)
lsh1	NP_592867.1	HYOU1-like_NBD	25..412	CDD:212672	93/408 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900