DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7182 and sks2

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_595438.1	Gene:	sks2 / 2540199	PomBaseID:	SPBC1709.05	Length:	613	Species:	Schizosaccharomyces pombe

Alignment Length:	433	Identity:	117/433 - (27%)
Similarity:	203/433 - (46%)	Gaps:	67/433 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            ||.:|.:..|:| |......|:|.|.||.|.:.:.:.:.....: .|..||.:.|..||..|
pombe    10 GIDLGTTYSCVA-VWETANVEIIPNDQGARTTPSFVAFTETERL-VGDAAKNQAAMNPRNTV--- 69

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDD------RVV-------- 121
                                     ||.:.|:.|..    .|.|.|.|      :|:
pombe    70 -------------------------FDAKRLIGRRY----EDPETQKDIKHWPFKVIDNNGIPTI 105

  Fly   122 -------TKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAG 179
                   .|..:|.:::..:|....|::..  ...::...||:::|:|:..|......||...||
pombe   106 EVNYLGEKKQFTAQEISAMVLTKMKEISEA--KLNKRVEKAVITVPAYFSDSQRAATKDAGAIAG 168

  Fly   180 FHVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGG 244
            .:|.:||.|||||.:.|.: :.::::.::||....||...|::...:|.|:|..|||.|...:||
pombe   169 LNVLRIINEPTAAAIAYGL-DAKSDKPKNVLIFDLGGGTFDVSLLKIQGGVFEVLATAGDTHLGG 232

  Fly   245 RQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNA 309
            ..|..|||:...:||:||.|:|..:..|::.::|:|....|..|:::..|.:.:|||.:|:|:::
pombe   233 EDFDNALVEHFIQEFKRKQKIDISDDPRALRRLRSACERAKRALSSVTQTTVEVDSLSNGIDFSS 297

  Fly   310 QMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKID--DIVLLGATMQIPKLQAAVGARFP 372
            .::|||||.:........|..:.:.::.::     :.|.|  ||||:|.:.:|||:|..|...|.
pombe   298 SITRARFEDINATTFKATIDPVAKVLKDSK-----VPKADVHDIVLVGGSTRIPKVQRLVSDFFD 357

  Fly   373 DAKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAE 415
            ...|:.|.:.||.||.|.|.||..|.:..:..  |.:|.::.:
pombe   358 GRALNKSINPDEAVAYGAAVQAAVLTNKADSD--KTQDLLLLD 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	112/410 (27%)
sks2	NP_595438.1	HSP70	8..613	CDD:278441	117/433 (27%)
		HSPA1-2_6-8-like_NBD	8..383	CDD:212675	114/414 (28%)
		BAR	<503..>603	CDD:299863
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810