DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7182 and Hyou1

DIOPT Version :9

Sequence 1:NP_001286979.1 Gene:CG7182 / 38944 FlyBaseID:FBgn0035878 Length:513 Species:Drosophila melanogaster
Sequence 2:NP_001029200.1 Gene:Hyou1 / 192235 RGDID:621146 Length:998 Species:Rattus norvegicus


Alignment Length:458 Identity:102/458 - (22%)
Similarity:184/458 - (40%) Gaps:104/458 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 IKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACL--------LWDGASEIECGLTAKQ------ 57
            :.:|:.::.:|.|:.....|::.||:..|.:...:        |.|.|:    |:..|.      
  Rat    38 VDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKENERFLGDSAA----GMAIKNPKATLR 98

  Fly    58 -------KMANRPRQAVAHS-FQLLQPKEELTEEKLSSALR-EIPCDFDKEELVFRMEHTVPSDR 113
                   |.|:.|..|:..| |    |:.||..:.....:| :|     ..:|.|..|       
  Rat    99 YFQHLLGKQADNPHVALYRSRF----PEHELNVDPQRQTVRFQI-----SPQLQFSPE------- 147

  Fly   114 EDQDDRVVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPI--AVLSIPSYYPASAYKLLADAAQ 176
                               |:|...|..:.....|..:.||  ||:::|:::..:..:.:..||:
  Rat   148 -------------------EVLGMVLNYSRSLAEDFAEQPIKDAVITVPAFFNQAERRAVLQAAR 193

  Fly   177 TAGFHVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFV-QLATF--- 237
            .||..|.|:|.:.||..|.|.:     .:|:.:     .....:|.||.:.:|..| .:.|:   
  Rat   194 MAGLKVLQLINDNTATALSYGV-----FRRKDI-----NSTAQNIMFYDMGSGSTVCTIVTYQTV 248

  Fly   238 -----GPFP------------IGGRQFTEALVQFICEEFRRKYK----LDPHESRRSVAKIRTAA 281
                 |..|            :||.:....|.:.:.:.|..:.|    .|..|:.|::||:...|
  Rat   249 KTKEAGTQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREA 313

  Fly   282 ANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQA-QKEHPGL 345
            ...|.:|:........|:.|||.||:.|:::|..||.|..    :|..::...|:|| |.....|
  Rat   314 NRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCA----DLFDRVPGPVQQALQSAEMSL 374

  Fly   346 SKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEED 410
            .:|:.::|:|...::||:|..:.......:|..:.:|||..|:|...||..|....:.:.....|
  Rat   375 DQIEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRD 439

  Fly   411 CVV 413
            .|:
  Rat   440 AVI 442

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7182NP_001286979.1 NBD_sugar-kinase_HSP70_actin 5..394 CDD:302596 97/437 (22%)
Hyou1NP_001029200.1 HSP70 35..700 CDD:278441 102/458 (22%)
HYOU1-like_NBD 36..424 CDD:212672 98/438 (22%)
RR_TM4-6 549..>706 CDD:283990
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 564..694
Prevents secretion from ER. /evidence=ECO:0000255 995..998
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0443
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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