Protein Alignment CG7182 and Hspa1l

DIOPT Version :10

• Sequence 1: NP_648212.1
• Gene: CG7182 / 38944
• FlyBaseID: FBgn0035878
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_038586.2
• Gene: Hspa1l / 15482
• MGIID: 96231
• Length: 641
• Species: Mus musculus
• Alignment Length: 531
• Identity: 144/531 - (27%)
• Similarity: 238/531 - (44%)
• Gaps: 95/531 - (17%)

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            ||.:|.:..|:. |...||.|:|||.||:|.:.:.:.:.....: .|..||.::|..|:..|
Mouse    10 GIDLGTTYSCVG-VFQHGKVEIIANDQGNRTTPSYVAFTDTERL-IGDAAKNQVAMNPQNTV--- 69

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRM--EHTVPSDREDQDDRVVT----------- 122
                                     ||.:.|:.|.  :..|.||.:....:|:.
Mouse    70 -------------------------FDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVMVSY 109

  Fly   123 ---------KDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTA 178
                     :::|:..:|.....||..|.|....       ||:::|:|:..|..:...||...|
Mouse   110 KGEKKAFYPEEISSMVLTKMKETAEAFLGHNVTN-------AVITVPAYFNDSQRQATKDAGVIA 167

  Fly   179 GFHVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIG 243
            |.:|.:||.|||||.:.|.: ::.:...||||....||...|::..::.:|:|...||.|...:|
Mouse   168 GLNVLRIINEPTAAAIAYGL-DKGSHGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLG 231

  Fly   244 GRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYN 308
            |..|...||....|||:||:|.|..:::|:|.::|||....|..|::.....|.||||.:|:|:.
Mouse   232 GEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFY 296

  Fly   309 AQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPD 373
            ..::|||||.|...:....::.:.:.:..|:.:.   :||.||||:|.:.:|||:|..:...|..
Mouse   297 TSITRARFEELCADLFRGTLEPVEKSLRDAKMDK---AKIHDIVLVGGSTRIPKVQKLLQDYFNG 358

  Fly   374 AKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG---- 434
            ..|:.|.:.||.||.|.|.||..|   :..:..|.:|.::.:            .|.|.||
Mouse   359 RDLNKSINPDEAVAYGAAVQAAIL---MGDKSEKVQDLLLLD------------VAPLSLGLETA 408

  Fly   435 ---------RGSVLPAK-IRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIP--EDG 487
                     |.|.:|.| .:|....|:...| .:.:.....:..|.::.:|.|...:.||  ..|
Mouse   409 GGVMTVLIKRNSTIPTKQTQIFTTYSDNQPG-VLIQVYEGERAMTRDNNLLGRFDLTGIPPAPRG 472

  Fly   488 LYQLEVEVDVD 498
            :.|:||..|:|
Mouse   473 VPQIEVTFDID 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_648212.1	ASKHA_ATPase-like	5..394	CDD:483947	117/409 (29%)
Hspa1l	NP_038586.2	PTZ00009	3..641	CDD:240227	144/531 (27%)
		Nucleotide-binding domain (NBD). /evidence=ECO:0000250|UniProtKB:P11142	3..388		120/421 (29%)
		Substrate-binding domain (SBD). /evidence=ECO:0000250|UniProtKB:P11142	396..511		22/101 (22%)