Protein Alignment CG7083 and PHAF1

DIOPT Version :9

• Sequence 1: NP_648211.1
• Gene: CG7083 / 38943
• FlyBaseID: FBgn0035877
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_006721347.1
• Gene: PHAF1 / 80262
• HGNCID: 29564
• Length: 519
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 231/528 - (43%)
• Similarity: 302/528 - (57%)
• Gaps: 121/528 - (22%)

  Fly     1 MLDLEIVPEISLGCDAWEFVLGMHFSQAIAIIQSQVGIIKGVQVLYSDTTPLGVDIIINLPQDGV 65
            |||||:|||.|||.:.|||.|||..:||:||:|....|||.||||||:.:||..|:|:||.|||:
Human     1 MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGI 65

  Fly    66 RLIFDPVSQRLKTIEVFNMKLVKLRYFGVYFNSPEVLPSIEQIEHSFGATHPG------------ 118
            :|:||..:||||.|||.::..|||:|.||:|||..:.|:||||:.||||||||
Human    66 KLMFDAFNQRLKVIEVCDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGGKPSPSDSSGHQ 130

  Fly   119 ----------------------------------------------------------------- 118
                                                                             
Human   131 WQFIAINLPGSAIPPHFLESGSHRIVGLVLGCEGNILPLVFNLVGQFRNKPQGRCCQSLLPARLV 195

  Fly   119 --------------------VYDAAKQLFALHFRGLSFYFPVDS-----KLHSGYAHGLSSLVFL 158
                                ||::|:|||.|:||||||.|.:||     |....:||||:||...
Human   196 YVSHFRCQSTMLFSSPPPPTVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIP 260

  Fly   159 NGASPVVSKMSLYAGSNVLENRVPSLPLSCYHRQMYLESATVLRTAFGHTKGLKLKLFTEGSGRA 223
            :||:  |.:|.:|:|:::.:.:.|.:||||:...:|.||..|||...| ..||:|:|...|.|..
Human   261 HGAT--VKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTG-PAGLRLRLLAAGCGPG 322

  Fly   224 L--EPRRQCFTRELLFGDSCEDVATSLGAPNRIFFKSEDKMKIHSSSVNRQAQSKRSDIFFNYFT 286
            |  :.:.:.|.|.:.|||||:||.:.||:|:::|:||||||||||.|.::|..||.:|.||||||
Human   323 LLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFT 387

  Fly   287 LGIDVLFDARTQTCKKFILHTNYPGHFNFNMYHRCEFQFLLQADHPSMSDSGHDLVTPTKQEHVN 351
            ||:|:||||.|...|||:||||||||:|||:||||||:..|     ::.....|..|.|
Human   388 LGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPL-----AIKKENADGQTET------ 441

  Fly   352 ITAYTKWDAISSALA-TSERPVVLHRASSTNTANPFGSTFCYGYQDLIFEVMPNSHIASVTLYNT 415
            .|.|:|||.|...|. ..|:||||||:||.|..||||||||:|.|.:|||||.|:||||||||
Human   442 CTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLY-- 504

  Fly   416 APPRQPAH 423
            .|||..:|
Human   505 GPPRPGSH 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7083	NP_648211.1	UPF0183	17..413	CDD:281646	214/500 (43%)
PHAF1	XP_006721347.1	UPF0183	15..504	CDD:281646	214/502 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148040
Domainoid	1	1.000	419	1.000	Domainoid score	I643
eggNOG	1	0.900	-	-		E1_KOG2819
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11864
Inparanoid	1	1.050	442	1.000	Inparanoid score	I1659
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55734
OrthoDB	1	1.010	-	-		D460044at33208
OrthoFinder	1	1.000	-	-		FOG0006084
OrthoInspector	1	1.000	-	-		oto88956
orthoMCL	1	0.900	-	-		OOG6_103934
Panther	1	1.100	-	-	LDO	PTHR13465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4382
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770