DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7083 and phaf1

DIOPT Version :9

Sequence 1:	NP_648211.1	Gene:	CG7083 / 38943	FlyBaseID:	FBgn0035877	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001076282.1	Gene:	phaf1 / 557406	ZFINID:	ZDB-GENE-060503-705	Length:	425	Species:	Danio rerio

Alignment Length:	433	Identity:	227/433 - (52%)
Similarity:	298/433 - (68%)	Gaps:	34/433 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLDLEIVPEISLGCDAWEFVLGMHFSQAIAIIQSQVGIIKGVQVLYSDTTPLGVDIIINLPQDGV 65
            |||||:|||.|||.:.|||.|||..:|||:|:|....|||.||||||:..||..|:|:||.|||:
Zfish     1 MLDLEVVPERSLGNEQWEFALGMPLAQAISILQKHCRIIKNVQVLYSEQMPLSHDLILNLTQDGI 65

  Fly    66 RLIFDPVSQRLKTIEVFNMKLVKLRYFGVYFNSPEVLPSIEQIEHSFGATHPGVYDAAKQLFALH 130
            :|:||..:||||.|||:::..|||:|.||:|||..:.|:||||:.||||||||||:||:|||.|:
Zfish    66 KLLFDACNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNAAEQLFHLN 130

  Fly   131 FRGLSFYFPVDS-----KLHSGYAHGLSSLVFLNGASPVVSKMSLYAGSNVLENRVPSLPLSCYH 190
            ||||||.|.:||     |....:||||:||...:||:  |.:|.:|:|:|:.|.:.|::||:|:.
Zfish   131 FRGLSFSFQLDSWSEAPKYEPNFAHGLASLQIPHGAT--VKRMYIYSGNNLQETKAPAMPLACFL 193

  Fly   191 RQMYLESATVLRTAFGHTKGLKLKLFTEGSG---------RALEPRRQCFTRELLFGDSCEDVAT 246
            ..:|.|...|||...| ..||||:|.|.|.|         ||:|       |.:.|||||:||.:
Zfish   194 GNVYAECVEVLRDGAG-PLGLKLRLLTAGCGPGVLADTKVRAVE-------RSIYFGDSCQDVLS 250

  Fly   247 SLGAPNRIFFKSEDKMKIHSSSVNRQAQSKRSDIFFNYFTLGIDVLFDARTQTCKKFILHTNYPG 311
            :||:|:::|:||||||||||.|.::|..||.:|.||||:.||:|:|||:.|...|||:||||:||
Zfish   251 ALGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYYILGVDILFDSTTHLVKKFVLHTNFPG 315

  Fly   312 HFNFNMYHRCEFQFLLQADHPSMSDSGHDLVTPTKQEHVNITAYTKWDAISSALA-TSERPVVLH 375
            |:|||:||||:|:..|     .:...|.|    ...|...:|.|:|||.|...|. ..|:|||||
Zfish   316 HYNFNIYHRCDFKIPL-----IIKKDGAD----AHSEDCILTTYSKWDQIQELLGHPMEKPVVLH 371

  Fly   376 RASSTNTANPFGSTFCYGYQDLIFEVMPNSHIASVTLYNTAPP 418
            |:||.|..||||||||:|.|.:|||||.|:||||||||....|
Zfish   372 RSSSANNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGAPRP 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7083	NP_648211.1	UPF0183	17..413	CDD:281646	213/410 (52%)
phaf1	NP_001076282.1	UPF0183	15..409	CDD:281646	213/412 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581954
Domainoid	1	1.000	416	1.000	Domainoid score	I634
eggNOG	1	0.900	-	-		E1_KOG2819
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11864
Inparanoid	1	1.050	438	1.000	Inparanoid score	I1649
OMA	1	1.010	-	-		QHG55734
OrthoDB	1	1.010	-	-		D460044at33208
OrthoFinder	1	1.000	-	-		FOG0006084
OrthoInspector	1	1.000	-	-		oto40468
orthoMCL	1	0.900	-	-		OOG6_103934
Panther	1	1.100	-	-	LDO	PTHR13465
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2868
SonicParanoid	1	1.000	-	-		X4382
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800