DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7083 and Phaf1

DIOPT Version :9

Sequence 1:	NP_648211.1	Gene:	CG7083 / 38943	FlyBaseID:	FBgn0035877	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001366027.1	Gene:	Phaf1 / 234678	MGIID:	2443049	Length:	452	Species:	Mus musculus

Alignment Length:	451	Identity:	233/451 - (51%)
Similarity:	306/451 - (67%)	Gaps:	34/451 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLDLEIVPEISLGCDAWEFVLGMHFSQAIAIIQSQVGIIKGVQVLYSDTTPLGVDIIINLPQDGV 65
            |||||:|||.|||.:.|||.|||..:||:||:|....||:.||||||:.:||..|:|:||.|||:
Mouse     1 MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIRNVQVLYSEQSPLSHDLILNLTQDGI 65

  Fly    66 RLIFDPVSQRLKTIEVFNMKLVKLRYFGVYFNSPEVLPSIEQIEHSFGATHPGVYDAAKQLFALH 130
            .|:||..:||||.|||..:..|||:|.||:|||..:.|:||||:.||||||||||::.:|||.|:
Mouse    66 TLLFDAFNQRLKVIEVCELTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSTEQLFHLN 130

  Fly   131 FRGLSFYFPVDS-----KLHSGYAHGLSSLVFLNGASPVVSKMSLYAGSNVLENRVPSLPLSCYH 190
            ||||||.|.:||     |....:||||:||...:||:  |.:|.:|:|:::.:.:.|.:||||:.
Mouse   131 FRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGAT--VKRMYIYSGNSLQDTKAPVMPLSCFL 193

  Fly   191 RQMYLESATVLRTAFGHTKGLKLKLFTEGSGRAL--EPRRQCFTRELLFGDSCEDVATSLGAPNR 253
            ..:|.||..|||...| ..||:|:|...|.|..:  :.:.:.|.|.:.|||||:||.:.||:|::
Mouse   194 GNVYAESVDVLRDGTG-PSGLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHK 257

  Fly   254 IFFKSEDKMKIHSSSVNRQAQSKRSDIFFNYFTLGIDVLFDARTQTCKKFILHTNYPGHFNFNMY 318
            :|:||||||||||.|.::|..||.:|.||||||||:|:||||.|...|||:||||||||:|||:|
Mouse   258 VFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIY 322

  Fly   319 HRCEFQFLLQ-----ADHPSMSDSG------------HDLVTPTK---QEHVNITAYTKWDAISS 363
            |||||:..|.     |...::.||.            |.|:.|..   |..: .|.|:|||:|..
Mouse   323 HRCEFKIPLAIKKAIAQRVAILDSACGWTYRPAQPSLHHLLFPENAGGQTEI-CTTYSKWDSIQE 386

  Fly   364 ALA-TSERPVVLHRASSTNTANPFGSTFCYGYQDLIFEVMPNSHIASVTLYNTAPPRQPAH 423
            .|. ..|:||||||:||.|..||||||||:|.|.:|||||.|:||||||||  .|||..||
Mouse   387 LLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLY--GPPRPGAH 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7083	NP_648211.1	UPF0183	17..413	CDD:281646	215/423 (51%)
Phaf1	NP_001366027.1	UPF0183	15..437	CDD:397645	215/425 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838133
Domainoid	1	1.000	412	1.000	Domainoid score	I684
eggNOG	1	0.900	-	-		E1_KOG2819
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11864
Inparanoid	1	1.050	438	1.000	Inparanoid score	I1667
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55734
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006084
OrthoInspector	1	1.000	-	-		oto92524
orthoMCL	1	0.900	-	-		OOG6_103934
Panther	1	1.100	-	-	LDO	PTHR13465
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2868
SonicParanoid	1	1.000	-	-		X4382
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790