Protein Alignment DNApol-alpha50 and PRI1

DIOPT Version :9

• Sequence 1: NP_523972.2
• Gene: DNApol-alpha50 / 38942
• FlyBaseID: FBgn0011762
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_012273.1
• Gene: PRI1 / 854825
• SGDID: S000001447
• Length: 409
• Species: Saccharomyces cerevisiae
• Alignment Length: 386
• Identity: 141/386 - (36%)
• Similarity: 207/386 - (53%)
• Gaps: 19/386 - (4%)

  Fly    17 TTAVHAYNPEVLQDMLPVYYRRLFPHLPFYRWLSYGSSEDAIFSNREISFTLQDDIYIRYLCFDT 81
            |.:|....|. ..|| ..||:.|:|....:.||::.........|||.:...:...|.||..|::
Yeast     2 TNSVKTNGPS-SSDM-EYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNS 64

  Fly    82 QAELEKEICSRNPIKIDIGPVMHSKPKNHRS--IPGGLTPVQRELVFDIDMTDYDEVRTCCSGAG 144
            ..:.:.:|...||.:.:||.: ::||...|.  :...|..:::||||||||.|||..|||||||.
Yeast    65 VQDFKAQIEKANPDRFEIGAI-YNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQ 128

  Fly   145 VCLKCWKFMVLAARVLDVALREDFGFEHIIWIFSGRRGIHCWVCDYQARHLDGRGRYAVAEYLNI 209
            ||.|||||:.||.::.:.|||||||::..||:||||||.||||.|.:||.|....|..|.:|:|:
Yeast   129 VCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNV 193

  Fly   210 ITYASFAGGNSPRCSMGDRPHH-SLKRALKIVEPMFEEIVLEDQNLFGTPK-GVTKLLNMVHDDA 272
            |     ...|:.:.....||:| .|.|:|:.::|.|..|:||:||.:...: .:..||..::|..
Yeast   194 I-----RDRNTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQ 253

  Fly   273 ARGELESYMQKNLEDGAHSRLVWESFIKYANSM-RTSTTSAWSRKLKNIVAEIQLGLLYPRLDIN 336
            ....|:.|...|....:..:  |....:.|.|: :.....:...||:....::.|..|||:||:.
Yeast   254 LIDSLKKYWLDNPRRSSKEK--WNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVE 316

  Fly   337 VTRGFNHLLKAPFCIHPATGKVCVPFSVSAVAKFDPTTVPTITQLLHEINAFDDKSKSYME 397
            ||:...||||||||||||||.||||...|    |.|...|.:..|..|:...:|.|.:.::
Yeast   317 VTKQTIHLLKAPFCIHPATGNVCVPIDES----FAPEKAPKLIDLQTEMEKNNDVSLTALQ 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-alpha50	NP_523972.2	AE_Prim_S	41..372	CDD:240130	127/335 (38%)
PRI1	NP_012273.1	primase_sml	13..362	CDD:273020	136/361 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343838
Domainoid	1	1.000	186	1.000	Domainoid score	I666
eggNOG	1	0.900	-	-		E1_COG1467
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H730
Inparanoid	1	1.050	235	1.000	Inparanoid score	I709
Isobase	1	0.950	-	0	Normalized mean entropy	S1232
OMA	1	1.010	-	-		QHG54298
OrthoFinder	1	1.000	-	-		FOG0004166
OrthoInspector	1	1.000	-	-		oto99605
orthoMCL	1	0.900	-	-		OOG6_101221
Panther	1	1.100	-	-	LDO	PTHR10536
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R980
SonicParanoid	1	1.000	-	-		X2917
TreeFam	1	0.960	-	-
	16	15.740