Protein Alignment DNApol-alpha50 and spp1

DIOPT Version :9

• Sequence 1: NP_523972.2
• Gene: DNApol-alpha50 / 38942
• FlyBaseID: FBgn0011762
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_593765.1
• Gene: spp1 / 2543323
• PomBaseID: SPAC6B12.10c
• Length: 454
• Species: Schizosaccharomyces pombe
• Alignment Length: 445
• Identity: 163/445 - (36%)
• Similarity: 244/445 - (54%)
• Gaps: 69/445 - (15%)

  Fly    35 YYRRLFPHLPFYRWLSYGSSEDAIFSNREISFTLQDDIYIRYLCFDTQAELEKEICSRNPIKIDI 99
            |||.|||....::||::|......|::||.:|||.:|.|||||.|....||:||..:..|.:.::
pombe    38 YYRHLFPWKYLFQWLNHGPVVTNDFAHREFAFTLPNDAYIRYLSFSNWEELKKEALNLCPSRFEV 102

  Fly   100 GPVMHSKPKNHRSI-PGGLTPVQRELVFDIDMTDYDEVRTCCSGAGVCLKCWKFMVLAARVLDVA 163
            |||..:.|::.::| .....|:::||||||||||||:||||||...:|.|||.|:.:|.:|||:.
pombe   103 GPVYSANPRDRKTIRKSTFHPLKKELVFDIDMTDYDDVRTCCSKTNICEKCWPFITIAVQVLDIC 167

  Fly   164 LREDFGFEHIIWIFSGRRGIHCWVCDYQARHLDGRGRYAVAEYLNIITYASFAGGNSPRCSMG-- 226
            ..|||||:||:|::|||||||.|:||..|..||.|.|..:|.||.::.      || |:..:.
pombe   168 FHEDFGFKHILWVYSGRRGIHAWICDEIACSLDDRSRRMIASYLQVVV------GN-PQGGVRLI 225

  Fly   227 ---DRP-HHSLKRALKIVEPMFEEIVLEDQNLFGTPKGVTKLLNMVHDDAARGELESYMQKNLED 287
               .|| |..|.|:|.|::..|.:||||||:.:.:.:|...||.::.|.    :|.|.::|.
pombe   226 NNLKRPLHPHLTRSLNILKSAFVKIVLEDQDPWASKEGAENLLKLLPDK----DLASALRKK--- 283

  Fly   288 GAHSRLVWESFIKYANSMRTSTTSAWSRKLKNIVA-----------------EIQLGLLYPRLDI 335
                   ||.      ....|:.:.|| .:..::|                 :|.|..||||||:
pombe   284 -------WEV------DPERSSKNKWS-DIDTVLASGSIASISPSVIAIAKQDIVLTYLYPRLDV 334

  Fly   336 NVTRGFNHLLKAPFCIHPATGKVCVPFSVSAVAKFDPTTVPTITQLLHEI--NAFDDK------S 392
            .|:|..|||||:|||:||.|.:||||..:..:..|:|..|||:..||.|:  |:.:|.      .
pombe   335 EVSRHLNHLLKSPFCVHPGTSRVCVPIDIERMDSFNPLKVPTVNDLLQELDKNSQNDNGHGPTME 399

  Fly   393 KSYMEAPEDKSRIKDHK----KTSMFKGVVVFEEFLRKLER-----SQKSASLQF 438
            .:..|..:|.:|.:.:|    .||:....:.|:.|..:|.:     .:|..:|:|
pombe   400 TNTTENQKDNARGQSNKGHGFSTSLNPYTLYFKSFSSQLFKETVGNKRKHENLEF 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-alpha50	NP_523972.2	AE_Prim_S	41..372	CDD:240130	137/354 (39%)
spp1	NP_593765.1	AE_Prim_S	44..371	CDD:240130	137/354 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	193	1.000	Domainoid score	I710
eggNOG	1	0.900	-	-		E1_COG1467
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H730
Inparanoid	1	1.050	282	1.000	Inparanoid score	I665
OMA	1	1.010	-	-		QHG54298
OrthoFinder	1	1.000	-	-		FOG0004166
OrthoInspector	1	1.000	-	-		oto101236
orthoMCL	1	0.900	-	-		OOG6_101221
Panther	1	1.100	-	-	LDO	PTHR10536
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R980
SonicParanoid	1	1.000	-	-		X2917
TreeFam	1	0.960	-	-
	14	13.860