Protein Alignment DNApol-alpha50 and Prim1

DIOPT Version :9

• Sequence 1: NP_523972.2
• Gene: DNApol-alpha50 / 38942
• FlyBaseID: FBgn0011762
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001291294.2
• Gene: Prim1 / 246327
• RGDID: 621380
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 175/426 - (41%)
• Similarity: 255/426 - (59%)
• Gaps: 31/426 - (7%)

  Fly    23 YNPEVLQDMLPVYYRRLFPHLPFYRWLSYGSSEDAIFSNREISFTLQDDIYIRYLCFDTQAELEK 87
            ::|..|.::|.:|||||||:..:||||:||......|.:||.||||:|||||||..|:.|::|||
  Rat     4 FDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEK 68

  Fly    88 EICSRNPIKIDIGPVMHSKPKNHRSIP-GGLTPVQRELVFDIDMTDYDEVRTCCSGAGVCLKCWK 151
            |:...||.|||||.|...:|..|.::. |.....::||||||||||||:||.|||.|.:|.|||.
  Rat    69 EMQKMNPYKIDIGAVYSHRPSQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWT 133

  Fly   152 FMVLAARVLDVALREDFGFEHIIWIFSGRRGIHCWVCDYQARHLDGRGRYAVAEYLNIITYASFA 216
            .|.:|.|::|.||:|||||:|.:|::|||||:||||||...|.|....|..:.|||::|     .
  Rat   134 LMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLI-----K 193

  Fly   217 GGN--SPRCSMGDRPHHSLKRALKIVEPMFEEIVLEDQNLFGTPKGVTKLLNM----VHDDAARG 275
            ||:  ..:..:.::.|..:::::.|::..|||..|.||::....:...|:|.:    |||:
  Rat   194 GGHDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVDQDILENKENWDKILALVPETVHDE---- 254

  Fly   276 ELESYMQKNLEDGAHSRLVWESFIKYAN---SMRTSTTSAWSRKLKNIVAEIQLGLLYPRLDINV 337
                 :||..:....|...||...|.|:   :.:......|      :..||.|...:|||||||
  Rat   255 -----LQKGFQRFHSSPQRWEYLRKVASAPQNTKNDKCGPW------LEWEIMLQYCFPRLDINV 308

  Fly   338 TRGFNHLLKAPFCIHPATGKVCVPFSVSAVAKFDPTTVPTITQLLHEINAFDDKSKSYMEAPED- 401
            ::|.|||||:||.:||.||::.||.....|.:|||..||||:.:..|::......|...|...|
  Rat   309 SKGVNHLLKSPFSVHPKTGRISVPIDFQKVDQFDPFVVPTISAICRELDVVSTTEKEKEENETDS 373

  Fly   402 KSRIKDHKKTSMFKGVVVFEEFLRKLERSQKSASLQ 437
            :.|::|:|:||:...|.|||:||..|::|:|.|.|:
  Rat   374 RHRVRDYKRTSLAPYVKVFEQFLENLDKSRKGALLK 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-alpha50	NP_523972.2	AE_Prim_S	41..372	CDD:240130	140/340 (41%)
Prim1	NP_001291294.2	AE_Prim_S	26..343	CDD:240130	139/336 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340895
Domainoid	1	1.000	161	1.000	Domainoid score	I3936
eggNOG	1	0.900	-	-		E1_COG1467
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3607
OMA	1	1.010	-	-		QHG54298
OrthoDB	1	1.010	-	-		D1346165at2759
OrthoFinder	1	1.000	-	-		FOG0004166
OrthoInspector	1	1.000	-	-		oto97064
orthoMCL	1	0.900	-	-		OOG6_101221
Panther	1	1.100	-	-	LDO	PTHR10536
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2917
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810