Protein Alignment DNApol-alpha50 and pri-1

DIOPT Version :9

• Sequence 1: NP_523972.2
• Gene: DNApol-alpha50 / 38942
• FlyBaseID: FBgn0011762
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001255015.1
• Gene: pri-1 / 176358
• WormBaseID: WBGene00004180
• Length: 410
• Species: Caenorhabditis elegans
• Alignment Length: 431
• Identity: 151/431 - (35%)
• Similarity: 220/431 - (51%)
• Gaps: 55/431 - (12%)

  Fly    22 AYNPEVLQDMLPVYYRRLFPHLPFYRWLSYGSSEDAIFSNREISFTLQDDIYIRYLCFDTQAELE 86
            :||...|...||:||:..||..||.:||.||.:....|:.||.:|.|.||::|||..::.:....
 Worm     2 SYNSIRLPQDLPIYYKNFFPVKPFTKWLRYGQNNGDYFNRREFAFILADDVHIRYRSYNDEHAFF 66

  Fly    87 KEICSRNPIKIDIGPVMHSKP---KNHRSIPGGLTPVQRELVFDIDMTDYDEVRTCCSGAGVCLK 148
            |.:.|.||.|:|||.|.:.:|   |.|.....    |:||||||||:||||.||.||..|.||.|
 Worm    67 KALSSTNPEKLDIGAVYNHEPINNKRHTDYQA----VERELVFDIDLTDYDPVRNCCKDATVCPK 127

  Fly   149 CWKFMVLAARVLDVALREDFGFEHIIWIFSGRRGIHCWVCDYQARHLDGRGRYAVAEYLNIITYA 213
            ||||||||.::||..|.:.|.|:..:|:||||||:||||.|.:||.|:...|.|:|..||:....
 Worm   128 CWKFMVLAVKILDFQLEDMFDFKARMWVFSGRRGVHCWVGDKKARMLNNYQRSAIATRLNLFKKN 192

  Fly   214 SFAGGNSPRCSMGDRP---HHSLKRALKIVEPMFEEIVLEDQNLFGTPKGVT--KLLNMVHDDAA 273
            ........|..|...|   ..:...|||  :.:||:::. ||........:|  |.::.|..|..
 Worm   193 GQCEVTEGRAKMTKVPPIVRDAFNVALK--DGVFEKMIY-DQGWLDKEDFITEYKFMSEVGRDDL 254

  Fly   274 RGELESY--------MQKNLEDGAHSRLV--WESFIKYANSMRTSTTSAWSRKLKNIVAEIQLGL 328
            |...|:|        |.:.|.|..:.:.:  .:..:.:....|.          :|.:....|..
 Worm   255 RSLSETYKTPQERWNMIRGLFDDDYRKSLSPKDGLLDFKMQGRD----------RNYLLYFVLQR 309

  Fly   329 LYPRLDINVTRGFNHLLKAPFCIHPATGKVCVPFSVSAVAKFDPTTVPTITQLLHEINAF----- 388
            .|||||:||:.|.|||||:||||||.||.|.||.:|..:.:||.:..|.|..::.|:::.
 Worm   310 CYPRLDVNVSTGTNHLLKSPFCIHPKTGNVAVPLNVGKIEEFDVSKCPRIDHVVEELSSLLAERG 374

  Fly   389 -----DDKSKSYMEAPEDKSRIKDHKKTSMFKGVVVFEEFL 424
                 |.|::.::.          :|..::...|..||:|:
 Worm   375 NDENEDSKNRKFLA----------YKHGALAPYVENFEKFV 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-alpha50	NP_523972.2	AE_Prim_S	41..372	CDD:240130	132/348 (38%)
pri-1	NP_001255015.1	AE_Prim_S	21..352	CDD:240130	131/347 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159382
Domainoid	1	1.000	155	1.000	Domainoid score	I2583
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H730
Inparanoid	1	1.050	245	1.000	Inparanoid score	I2049
Isobase	1	0.950	-	0	Normalized mean entropy	S1232
OMA	1	1.010	-	-		QHG54298
OrthoDB	1	1.010	-	-		D1346165at2759
OrthoFinder	1	1.000	-	-		FOG0004166
OrthoInspector	1	1.000	-	-		otm14410
orthoMCL	1	0.900	-	-		OOG6_101221
Panther	1	1.100	-	-	LDO	PTHR10536
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R980
SonicParanoid	1	1.000	-	-		X2917
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890