Protein Alignment Pex2 and PEX2

DIOPT Version :10

• Sequence 1: NP_648210.1
• Gene: Pex2 / 38941
• FlyBaseID: FBgn0035876
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_000309.2
• Gene: PEX2 / 5828
• HGNCID: 9717
• Length: 305
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 89/299 - (29%)
• Similarity: 148/299 - (49%)
• Gaps: 40/299 - (13%)

  Fly     7 VPRVNQIDAIYLNKDIARLIRDNLLENLQAISPVLFIKIQPELDLIIQSAIWFGSVGKRCSTFGQ 71
            |.|::|:||:.|||.:.:|:.....:......|.|..:.:||:...:...:|..::..:.:|.||
Human    14 VLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKACLWVFLWRFTIYSKNATVGQ 78

  Fly    72 QLLVLAYD--------AEKLTVSRLVLHFILTVLPGYVKSWEERR---LTRRVEWFS-----EAI 120
            .:|.:.|.        .:..:.::.:.:.:.|:    ...|.|.|   |.|.....|     :.:
Human    79 SVLNIKYKNDFSPNLRYQPPSKNQKIWYAVCTI----GGRWLEERCYDLFRNHHLASFGKVKQCV 139

  Fly   121 MWVENSALILNILNYFRFLKTGRKPTLVDYLLGLDYISLRNNQRRDIGYKYLTRELLWGGFMEIL 185
            .:|.....:..::|:..||:.|:..||.:.|||:..:..:.....::|::|:.|||||.||.|.|
Human   140 NFVIGLLKLGGLINFLIFLQRGKFATLTERLLGIHSVFCKPQNICEVGFEYMNRELLWHGFAEFL 204

  Fly   186 GLVLPIINFRKLQRVLKSWTFSGRRLEDRDGPAFLAPQM--TLSTT---CTFCGERPTLPHHMGC 245
            ..:||:||.:||:..|.||..          |...||..  ||:|:   |..|||.||:||.:||
Human   205 IFLLPLINVQKLKAKLSSWCI----------PLTGAPNSDNTLATSGKECALCGEWPTMPHTIGC 259

  Fly   246 GHIYCYYCLNANVLTDASFCCPNCG----SACP-ESGIQ 279
            .||:||:|..::.|.|..|.||.||    |..| :|||:
Human   260 EHIFCYFCAKSSFLFDVYFTCPKCGTEVHSLQPLKSGIE 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex2	NP_648210.1	Pex2_Pex12	22..207	CDD:398431	48/200 (24%)
		RING-HC_PEX2	227..273	CDD:438189	24/52 (46%)
PEX2	NP_000309.2	Pex2_Pex12	27..224	CDD:398431	48/200 (24%)
		RING-HC_PEX2	242..288	CDD:438189	22/45 (49%)