Protein Alignment Cpsf6 and Cpsf6

DIOPT Version :9

• Sequence 1: NP_648206.1
• Gene: Cpsf6 / 38937
• FlyBaseID: FBgn0035872
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_006241434.1
• Gene: Cpsf6 / 299811
• RGDID: 1304640
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 715
• Identity: 289/715 - (40%)
• Similarity: 366/715 - (51%)
• Gaps: 192/715 - (26%)

  Fly     1 MADVV--LDLYAEDLDKDFAGQAQDEFGG-DGVDLYDDIGGPTESAASGGGGGG-------TPSA 55
            |||.|  :|:|| |:.::|..:|  |:|| |.:|||||:..|  ||.:|.....       .|:.
  Rat     1 MADGVDHIDIYA-DVGEEFNQEA--EYGGHDQIDLYDDVISP--SANNGDAPEDRDYMDTLPPTV 60

  Fly    56 DGAAGPGSGEPGERNSGGPNGVYHQSSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGVSD 120
            ....|.|:         .||.||..:        .:|..||:|||||||||:|:..::..:||:|
  Rat    61 GDDVGKGA---------APNVVYTYT--------GKRIALYIGNLTWWTTDEDLTEAVHSLGVND 108

  Fly   121 LQEVKFFENRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKT 185
            :.|:||||||||||||||:::.:|||:|.:.::|.|||:|:|||.||||..:||.|:||| :|..
  Rat   109 ILEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFE-MQSR 172

  Fly   186 RPVPPPQQNGPPRGPAPPSMGG------------GPMPTGHPGGPQGGGP--PGHPP-------- 228
            :.....|.:|  .|.|.|..||            |..|...|||.:..||  ||.||
  Rat   173 KTTQSGQMSG--EGKAGPPGGGSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPGNLI 235

  Fly   229 ----RGMNSIMQPGQYRPQHM----SQVPQVGGPNSG--PPRMQPPMHPQGGLMGNQQPPPRYPS 283
                :|...:....:. |.||    .::| :.|..:|  |||  ||:.|.|. .|...|||
  Rat   236 KHLVKGTRPLFLETRI-PWHMGHSIEEIP-IFGLKAGQTPPR--PPLGPPGP-PGPPGPPP---- 291

  Fly   284 AQGQWPGQRPGGPRPGPPN---GPPQRPMFQGGPMGMPVRG--PAGPDWRRPPMHGGFPPQGPP- 342
                 |||....|..||||   .||...:|.|.|.|.|..|  |.||.   ||:.|..||.|||
  Rat   292 -----PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP---PPVPGYGPPPGPPP 348

  Fly   343 --RGLPPAPGPGGPHGAPAPHVNPAFFNQPGGP-------AQHPGMGGPPHGAPGPQPGMN---M 395
              :|.||.|||..|              :|.||       |..|.:.|||.|||.|.|.:|   .
  Rat   349 PQQGPPPPPGPFPP--------------RPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF 399

  Fly   396 PP--QQGMNMTPQHGPPPQFAQHGPRGPWPPPQGK----PPGPFPDPQQMGPQLTEVEFEEVMSR 454
            ||  ..||..:...||||.    .|.|. |||..:    |||...|..:  ..|:|.||||:|:|
  Rat   400 PPPTNSGMPTSDSRGPPPT----DPYGR-PPPYDRGDYGPPGREMDTAR--TPLSEAEFEEIMNR 457

  Fly   455 NRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSY 519
            ||.:|||||:||||||:||:|.||||||||||||||||||:.|:|||:|||||||.|||||:|||
  Rat   458 NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSY 522

  Fly   520 NRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGSYRERSRSRERERQAPDHY 584
            .                    |.||.|||||||:..|.||:.|     |.:||||:|.   .|:|
  Rat   523 G--------------------SGSRRRERSRERDHSRSREKSR-----RHKSRSRDRH---DDYY 559

  Fly   585 RDDSRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRREEHR 649
            |:.||                          :|||:         |||||||:|||||:|...||
  Rat   560 RERSR--------------------------ERERH---------RDRDRDRDRERDREREYRHR 589

  Fly   650  649
              Rat   590  589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf6	NP_648206.1	RRM_CFIm68	94..170	CDD:241087	45/75 (60%)
Cpsf6	XP_006241434.1	RRM_CFIm68	82..158	CDD:241087	37/75 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337247
Domainoid	1	1.000	271	1.000	Domainoid score	I1748
eggNOG	1	0.900	-	-		E1_KOG4849
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	390	1.000	Inparanoid score	I1930
OMA	1	1.010	-	-		QHG48498
OrthoDB	1	1.010	-	-		D1016696at2759
OrthoFinder	1	1.000	-	-		FOG0003643
OrthoInspector	1	1.000	-	-		otm45582
orthoMCL	1	0.900	-	-		OOG6_108776
Panther	1	1.100	-	-	LDO	PTHR23204
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2511
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860