Protein Alignment Cpsf6 and Cpsf6

DIOPT Version :10

• Sequence 1: NP_648206.1
• Gene: Cpsf6 / 38937
• FlyBaseID: FBgn0035872
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_061503080.1
• Gene: Cpsf6 / 1274745
• VectorBaseID: AGAMI1_007231
• Length: 645
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 408/711 - (57%)
• Similarity: 460/711 - (64%)
• Gaps: 125/711 - (17%)

  Fly     1 MAD-VVLDLYAEDLDKDFAGQAQDEFGGDGVDLYDDIGGPTESAASGGGGGGTPSADGAAGPGSG 64
            ||| |.:||||:|||:|:| |..|:||||..|||||:..|:....:.|.|   ||.|...|..:
Mosquito     1 MADGVEIDLYADDLDQDYA-QNNDDFGGDSGDLYDDVIVPSGDRNNAGRG---PSMDRGDGVDT- 60

  Fly    65 EPGERNSGGPNGVYHQSSGSLTPT-MNRRYQLYVGNLTWWTTDQDIANSLRDIGVSDLQEVKFFE 128
                      ||.||...|:.:.: :.||:|||||||.||||||||.:|:.::||:|.|||||||
Mosquito    61 ----------NGSYHHHPGAWSLSHIPRRHQLYVGNLPWWTTDQDITDSVAEVGVNDFQEVKFFE 115

  Fly   129 NRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPP-PQ 192
            ||||||||||.|||||||:|:|.|:::|||||:|||.||||.|:||||.||||.|||||.|| |.
Mosquito   116 NRANGQSKGFCVISLGSENSMRLVMERLPKKELHGQNPVVTLPTKQALNQFESQQKTRPTPPAPG 180

  Fly   193 QNGPPRGPAP----------------PSMG--GGPMPTGHPGGPQG----GGPPGHPPRGMNSIM 235
            |:..||.|.|                |.||  ||| |.|.||||.|    |||.|..||.||..|
Mosquito   181 QSNGPRPPVPGMPMGGPGGPGGGHGGPGMGGPGGP-PGGGPGGPGGPGGMGGPGGPQPRMMNPNM 244

  Fly   236 QPGQYRPQ-HMSQVPQVGGPN---SGPPRMQ-PPMHPQGGLMGNQQPPPRYPSAQGQWPG-QRPG 294
            .||...|. |||....:.||:   .||||.| |||| ||.  |..|.|||:.: |.||.| .|..
Mosquito   245 PPGMRPPHPHMSGPMHMQGPHGGPGGPPRPQGPPMH-QGN--GPPQQPPRFQN-QNQWNGPPRMN 305

  Fly   295 GPRPGPPNGP---PQRP-MFQGGPMGMPVRGPAGPDWRRPPMHGGFPP-------QGPP--RGLP 346
            |||||.|.||   ..|| ||||.|.||| |||. |:|.|||||||:||       ||||  :|.|
Mosquito   306 GPRPGGPGGPGPMQHRPQMFQGPPNGMP-RGPR-PEWNRPPMHGGYPPGHPGGPGQGPPHMQGGP 368

  Fly   347 PAP---------GPGGPHGAPAPHVNPAFFNQPGGPAQHPGMG---GPPHGAPGPQPGMNMPPQQ 399
            ..|         ||.||.| ||||||||||||.|||..||..|   |||||..|...|   |||
Mosquito   369 HGPRAPHHGSMGGPPGPQG-PAPHVNPAFFNQGGGPPNHPNGGGPVGPPHGPQGQGGG---PPQ- 428

  Fly   400 GMNMTPQHGPPPQFAQHGPRGPWPPPQGKPPGP---FPDPQQMGPQLTEVEFEEVMSRNRTVSSS 461
              :..||.|..|:      .||||...|||||.   ||:...:.|||:|.||||:|:||||||||
Mosquito   429 --HFNPQGGGAPR------GGPWPVQGGKPPGAPGGFPEHPVITPQLSEAEFEEIMTRNRTVSSS 485

  Fly   462 AIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNRRERSR 526
            |||||||||||||||||.|||.||||||||||||.||||||||.||||||||||||||.||||||
Mosquito   486 AIARAVSDAAAGEYSSATETLETAISLIKQSKVAQDERCKILIVSLQDTLHGIEAKSYTRRERSR 550

  Fly   527 SRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGSYRERSRSRERERQAPDHYRDDSRSV 591
            ||||||| ||||||||||||||||:|||:|:|:|:||            ||       ||.||..
Mosquito   551 SRERSHR-RQRRERSTSRYRERSRDRERERERDRDRD------------RE-------RDGSRRS 595

  Fly   592 RPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRREEHRSRH 652
            ||||||||....|.:: ||||||.| :||||||||         |||:|||:|||:|||||
Mosquito   596 RPRKSPEPATDNATDS-SSKRYYND-DRYRSSDRE---------RERDRDRERREDHRSRH 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf6	NP_648206.1	RRM_CFIm68	94..170	CDD:410048	57/75 (76%)
		PABP-1234	<131..287	CDD:130689	99/183 (54%)
		Med15	159..>439	CDD:312941	169/336 (50%)
Cpsf6	XP_061503080.1	None