DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sbp2 and SECISBP2L

DIOPT Version :10

Sequence 1:NP_648204.1 Gene:Sbp2 / 38934 FlyBaseID:FBgn0087039 Length:313 Species:Drosophila melanogaster
Sequence 2:NP_001180418.1 Gene:SECISBP2L / 9728 HGNCID:28997 Length:1101 Species:Homo sapiens


Alignment Length:355 Identity:93/355 - (26%)
Similarity:153/355 - (43%) Gaps:61/355 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 KITPRSSKYKNQHRKREQQTSLLDFVIKPRPKTQRQTKAHKLQKT----HLAITRGSYIV----- 74
            |:....||...:..|...|..|.| ::....|.|:..||.::..|    :..:|..|:..     
Human   471 KLQEALSKAAGKKNKTPVQLDLGD-MLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTN 534

  Fly    75 YKP----------------------KGKTRLDPK-KKITRLKKSVRVYRTSKKAEREVAENDL-- 114
            .||                      |||.:...| |:.|.|||.:...|..||....|..|.|  
Human   535 RKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVDHNLLGS 599

  Fly   115 -----------EGVP--VVGQDIN----PNAIPLEQQVQNLSLSKTPAP---------NNPSQAK 153
                       :.:|  :|.|:..    |:...|....||.....||..         .:|..:.
Human   600 EEPTEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASS 664

  Fly   154 TVHAIHSRRFRSYCDNCTRPRLKELSTQLLRDLDRFQKRAFAKNEIKARAHPRLVLGVREALARL 218
            |:..|||:|||.||:......:.|..|.||::|..||:|.:.|:.::|:|..|||:|:||....:
Human   665 TITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHM 729

  Fly   219 RINKVKLLFLATDCEICPGESGLDATIEGLKFQCQQQQVPYCFPLLRRELSYALQKRAQICCVAI 283
            ::||:|.:.::.:||....:.|||..:..:....::|::|:.|.|.|:.|...:.|...:..|.|
Human   730 KLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGI 794

  Fly   284 LDFDGANATYADLLNEIEDARAEYKRRTAS 313
            .::.||.:.:..|:...|:||..||...|:
Human   795 FNYFGAESLFNKLVELTEEARKAYKDMVAA 824

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sbp2NP_648204.1 Ribosomal_L7Ae 200..290 CDD:426153 26/89 (29%)
SECISBP2LNP_001180418.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 154..206
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 240..295
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 320..387
Ribosomal_L7Ae 702..804 CDD:426153 29/101 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 884..1010
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1030..1101
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.