DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sbp2 and SECISBP2

DIOPT Version :10

Sequence 1:NP_648204.1 Gene:Sbp2 / 38934 FlyBaseID:FBgn0087039 Length:313 Species:Drosophila melanogaster
Sequence 2:NP_076982.3 Gene:SECISBP2 / 79048 HGNCID:30972 Length:854 Species:Homo sapiens


Alignment Length:342 Identity:92/342 - (26%)
Similarity:146/342 - (42%) Gaps:46/342 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 IRRSRNQDVQDTAIKITPRSSKYKNQHRKREQQ-----TSLLDFVIKPRPKTQRQTKAHKLQKTH 64
            :::|:.....|....:|....|..:||.|:..:     ...:..:.|.....:|..:..:::..|
Human   441 VKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPH 505

  Fly    65 LAITRGSYIVYKPKGKTRLDPK-KKITRLKKSVRVYRTSKKAEREVAEN---------DLEGVPV 119
            ..:...:.::  .|||.|..|| ||.|.|||.:...|..:|  :.:.||         |.:....
Human   506 NPLDSSAPLM--KKGKQREIPKAKKPTSLKKIILKERQERK--QRLQENAVSPAFTSDDTQDGES 566

  Fly   120 VGQDINPNAIPLEQQVQNLSLSKTP-----------------------APNNPSQAKTVHAIHSR 161
            .|.|..|....|........|..||                       |||:.:..|    ||||
Human   567 GGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPK----IHSR 627

  Fly   162 RFRSYCDNCTRPRLKELSTQLLRDLDRFQKRAFAKNEIKARAHPRLVLGVREALARLRINKVKLL 226
            |||.||.......:....|.||::|.|||.|.:.|:.:||:...|||||:||.|..|::.|:|.:
Human   628 RFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCV 692

  Fly   227 FLATDCEICPGESGLDATIEGLKFQCQQQQVPYCFPLLRRELSYALQKRAQICCVAILDFDGANA 291
            .::.:||....:.|||.|:..:.....:|.:|:.|.|.|:.|..:|.|...:..|.|..:|||..
Human   693 IISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQD 757

  Fly   292 TYADLLNEIEDARAEYK 308
            .:..::.....||..||
Human   758 QFHKMVELTVAARQAYK 774

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sbp2NP_648204.1 Ribosomal_L7Ae 200..290 CDD:426153 31/89 (35%)
SECISBP2NP_076982.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 332..351
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..394
Nuclear localization signal. /evidence=ECO:0000255 380..387
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 417..445 0/3 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 488..619 29/134 (22%)
Ribosomal_L7Ae 657..757 CDD:426153 34/99 (34%)
RNA-binding. /evidence=ECO:0000255 673..694 10/20 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 787..812
Blue background indicates that the domain is not in the aligned region.

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