Protein Alignment CG7194 and ITPRIPL2

DIOPT Version :10

• Sequence 1: NP_648203.1
• Gene: CG7194 / 38933
• FlyBaseID: FBgn0035868
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_001030013.1
• Gene: ITPRIPL2 / 162073
• HGNCID: 27257
• Length: 535
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 80/365 - (21%)
• Similarity: 118/365 - (32%)
• Gaps: 143/365 - (39%)

  Fly    35 VVDELKRVDK---------------TFRQVFDGLSLGGSYLDRVKLNLPDEFDLHMKLKFP--FD 82
            :|.||.|..:               .||.  |.:.:|.:| ::.|:..||.||:.:.|:.|  ..
Human   126 IVGELVRAGRARGSPGLIPGGALALAFRG--DFIQVGSAY-EQHKIRRPDSFDVLVPLRLPPLVA 187

  Fly    83 IRPTRIDQG-----------FIYLEADLTVINPQRIHRIVLQDWLR------NAFRKVFRSNQTI 130
            :.|..:.:.           ...|:|..:.......|      |||      :||....|..:.:
Human   188 LEPRSLGEEPALAPAFRGCFLCALKAPPSPSGASGGH------WLRDCKPFADAFCVDVRGRRHL 246

  Fly   131 ATT----------SNRVYKLTYTLEG-------------------------YGCAHTILAVCGSR 160
            :.|          ...:..:.|:|||                         |||....:||
Human   247 SATLVLRWFQSHLQRSLATVRYSLEGRCRVTLTPGGLEQPPTLHILPCRTDYGCCRLSMAV---- 307

  Fly   161 SISFDLVPAFEFSGSQWPFDICPVPADVSNNWPWFAIP----------------QQK-----KKS 204
                .|:||......  .|.:.|.|..:.:. |...:|                :||     ::.
Human   308 ----RLIPAVHLGDG--VFLVAPPPPPLPSA-PLLELPEGLRAEALWGVNTARQEQKLLSWLQER 365

  Fly   205 AKPRTTFMVCAPHWEREIMKGKDNLKNVLRLMKGLRDAHARKLPH---------LSSYMLKTVLL 260
            |.|...::.|                  |:|:|.|||..||.|..         ||||:||||||
Human   366 AAPGACYLKC------------------LQLLKALRDLGARGLDSAAATQWGRILSSYVLKTVLL 412

  Fly   261 HRL-----ESADW-ERDLGTLLVEMWSHLVDHLRARRLEF 294
            ..|     ....| |..||..|.|:...|.|.|..|...|
Human   413 AVLLRKGAPGQGWDEEHLGRCLEELVQFLRDCLLRRHTLF 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7194	NP_648203.1	Mab-21	59..225	CDD:460873	41/240 (17%)
		Mab-21_C	228..312	CDD:466416	31/82 (38%)
ITPRIPL2	NP_001030013.1	Mab-21	163..>266	CDD:460873	19/109 (17%)
		Mab-21_C	374..>453	CDD:466416	32/97 (33%)