DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arl5 and Arl5a

DIOPT Version :9

Sequence 1:	NP_648201.1	Gene:	Arl5 / 38931	FlyBaseID:	FBgn0035866	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_892039.1	Gene:	Arl5a / 75423	MGIID:	1922673	Length:	179	Species:	Mus musculus

Alignment Length:	177	Identity:	129/177 - (72%)
Similarity:	157/177 - (88%)	Gaps:	0/177 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLLLSRLWRMFGNEEHKLVMVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVW 65
            ||:|.:|:||:|.::|||:::|||||||||||||||.|||||||||||||||||:|..|..||:|
Mouse     1 MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVVNNTRFLMW 65

  Fly    66 DLGGQQSLRAAWSTYYTNTELVIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLK 130
            |:|||:|||.:|:|||||||.||:|:|||||||::|||||||:||.||||.||.||::|||||:|
Mouse    66 DIGGQESLRPSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQDVK 130

  Fly   131 GSMSAAEISRQLDLTSIKKHQWHIQACCALTGEGLYQGLEWIVQRIK 177
            ..|:.||||:.|.|||||.||||||||||||||||.|||||::.|:|
Mouse   131 ECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLK 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl5	NP_648201.1	Arl5_Arl8	3..175	CDD:133353	125/171 (73%)
Arl5a	NP_892039.1	Arl5_Arl8	3..175	CDD:133353	125/171 (73%)
Arl5a	NP_892039.1	Ras	18..164	CDD:278499	110/145 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	269	1.000	Domainoid score	I1832
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100572
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2855
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53833
OrthoDB	1	1.010	-	-		D1417432at2759
OrthoFinder	1	1.000	-	-		FOG0001602
OrthoInspector	1	1.000	-	-		otm42412
orthoMCL	1	0.900	-	-		OOG6_104179
Panther	1	1.100	-	-	O	PTHR11711
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2407
SonicParanoid	1	1.000	-	-		X1008
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.870