DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arl5 and arl5a

DIOPT Version :9

Sequence 1:	NP_648201.1	Gene:	Arl5 / 38931	FlyBaseID:	FBgn0035866	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_001002339.1	Gene:	arl5a / 436611	ZFINID:	ZDB-GENE-040718-28	Length:	179	Species:	Danio rerio

Alignment Length:	177	Identity:	128/177 - (72%)
Similarity:	160/177 - (90%)	Gaps:	0/177 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLLLSRLWRMFGNEEHKLVMVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVW 65
            ||::.::|||:|.::|||:::|||||||||||||||.|||||||||||||||||:|..|.|||:|
Zfish     1 MGIIFTKLWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVVNNTHFLMW 65

  Fly    66 DLGGQQSLRAAWSTYYTNTELVIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLK 130
            |:|||:|||::|:|||||||.||:|:|||||||::||||||||||.||||.||.||::|||||:|
Zfish    66 DIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYRMLAHEDLKKAGLLIFANKQDVK 130

  Fly   131 GSMSAAEISRQLDLTSIKKHQWHIQACCALTGEGLYQGLEWIVQRIK 177
            |.::.||||:.|.|||:|.||||||||||||||||.|||||::.|::
Zfish   131 GCLTVAEISQSLQLTSVKDHQWHIQACCALTGEGLCQGLEWMMSRLR 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl5	NP_648201.1	Arl5_Arl8	3..175	CDD:133353	125/171 (73%)
arl5a	NP_001002339.1	Arl5_Arl8	3..175	CDD:133353	125/171 (73%)
arl5a	NP_001002339.1	SAR	8..172	CDD:197556	124/163 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	265	1.000	Domainoid score	I1854
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100572
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2879
OMA	1	1.010	-	-		QHG53833
OrthoDB	1	1.010	-	-		D1417432at2759
OrthoFinder	1	1.000	-	-		FOG0001602
OrthoInspector	1	1.000	-	-		otm26177
orthoMCL	1	0.900	-	-		OOG6_104179
Panther	1	1.100	-	-	O	PTHR11711
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2407
SonicParanoid	1	1.000	-	-		X1008
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870