DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl5 and ARL5C

DIOPT Version :9

Sequence 1:	NP_648201.1	Gene:	Arl5 / 38931	FlyBaseID:	FBgn0035866	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_001137440.1	Gene:	ARL5C / 390790	HGNCID:	31111	Length:	179	Species:	Homo sapiens

Alignment Length:	172	Identity:	103/172 - (59%)
Similarity:	132/172 - (76%)	Gaps:	0/172 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLLLSRLWRMFGNEEHKLVMVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVW 65
            ||.|:::|..:|||:||.:::|||||.|||||||:||.|||||..|||||||||::....||.:|
Human     1 MGQLIAKLMSIFGNQEHTVIIVGLDNEGKTTILYRFLTNEVVHMCPTIGSNVEEIILPKTHFFMW 65

  Fly    66 DLGGQQSLRAAWSTYYTNTELVIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLK 130
            |:...::|...|:|||:|||.:|:|||||||:||..||||||:||.||.|..||:|::|||||:|
Human    66 DIVRPEALSFIWNTYYSNTEFIILVIDSTDRDRLLTTREELYKMLAHEALQDASVLIFANKQDVK 130

  Fly   131 GSMSAAEISRQLDLTSIKKHQWHIQACCALTGEGLYQGLEWI 172
            .||...|||..|.|::||.|.||||.|||||.|||...|:|:
Human   131 DSMRMVEISHFLTLSTIKDHSWHIQGCCALTREGLPARLQWM 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl5	NP_648201.1	Arl5_Arl8	3..175	CDD:133353	101/170 (59%)
ARL5C	NP_001137440.1	P-loop_NTPase	3..175	CDD:304359	101/170 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53833
OrthoDB	1	1.010	-	-		D1417432at2759
OrthoFinder	1	1.000	-	-		FOG0001602
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11711
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1008
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.890