DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl5 and TRIM23

DIOPT Version :9

Sequence 1:	NP_648201.1	Gene:	Arl5 / 38931	FlyBaseID:	FBgn0035866	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_001647.1	Gene:	TRIM23 / 373	HGNCID:	660	Length:	574	Species:	Homo sapiens

Alignment Length:	165	Identity:	71/165 - (43%)
Similarity:	111/165 - (67%)	Gaps:	7/165 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EHKLVMVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVWDLGGQQSLRAAWSTY 80
            |.::|.:|||.|||||||::...:|.:...||||.|||.|.::|:.|.:||:||:..||..|..|
Human   404 EIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHY 468

  Fly    81 YTNTELVIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLKGSMSAAEISRQLDLT 145
            |.||:.|:.|:||:.|:|::....||.::|..::|..|.||::|||||:.|::|..||:   :|.
Human   469 YLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEIT---ELL 530

  Fly   146 SIKK----HQWHIQACCALTGEGLYQGLEWIVQRI 176
            |:.|    ..|:||.|.|.:|.|||:||:|:.:::
Human   531 SLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQL 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl5	NP_648201.1	Arl5_Arl8	3..175	CDD:133353	71/162 (44%)
TRIM23	NP_001647.1	mRING-HC-C3HC3D_TRIM23_C-IX	28..77	CDD:319559
		Bbox2_TRIM23_C-IX_rpt1	123..172	CDD:380831
		Bbox2_TRIM23_C-IX_rpt2	174..223	CDD:380832
		BBC	226..370	CDD:128778
		ARF-like	390..574		71/165 (43%)
		ARD1	406..574	CDD:206723	70/163 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810