Protein Alignment Rab19 and RAB3D

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_004274.1
• Gene: RAB3D / 9545
• HGNCID: 9779
• Length: 219
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 82/207 - (39%)
• Similarity: 128/207 - (61%)
• Gaps: 12/207 - (5%)

  Fly    15 EEHFDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAG 79
            :::||::||::|||:...|||..:.|:...::.....:|:|:||.:||:....|:||||||||||
Human    16 DQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAG 80

  Fly    80 QERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREV 144
            |||:||||.:|||.|.|.|::|||..:.||:.:|.|..:::.|:..|..:||||||||||::|.|
Human    81 QERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVV 145

  Fly   145 DFEEARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGKPL 209
            ..|:.|::...:....|  |.|||||:||:..|..|.:.:..:  .|...|...::.:.|:|..:
Human   146 PAEDGRRLADDLGFEFF--EASAKENINVKQVFERLVDVICEK--MNESLEPSSSSGSNGKGPAV 206

  Fly   210 --------KSCS 213
                    .|||
Human   207 GDAPAPQPSSCS 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	74/164 (45%)
RAB3D	NP_004274.1	Rab3	22..186	CDD:206657	73/165 (44%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		2/8 (25%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		11/15 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..219		6/29 (21%)