Protein Alignment Rab19 and RAB9A

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 73/205 - (35%)
• Similarity: 111/205 - (54%)
• Gaps: 24/205 - (11%)

  Fly    21 LFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRT 85
            |||::|:||.|.||:.:::|:.|..:..:..:||||:|..|.:.|:|..:.:||||||||||||:
Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71

  Fly    86 ITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYT----ASNVLIILVGNKCDLEEQREVDF 146
            :...:||.::..|:.:.:....||.||..|.:|...|.    ..:...:::|||.|:.| |:|..
Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISE-RQVST 135

  Fly   147 EEARQMCQYIPEILFVMETSAKENMNVEDAF-----RCLANELKRQH----DANNVEEVPENTIT 202
            |||:..|:...:..: .|||||:..||..||     |.||.|.:..|    |..|:...|
Human   136 EEAQAWCRDNGDYPY-FETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVNLHRKP----- 194

  Fly   203 LGQGKPLKSC 212
                ||..||
Human   195 ----KPSSSC 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	64/171 (37%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	61/166 (37%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		2/10 (20%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		7/13 (54%)