Protein Alignment Rab19 and Rab35

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_937806.1
• Gene: Rab35 / 77407
• MGIID: 1924657
• Length: 201
• Species: Mus musculus
• Alignment Length: 209
• Identity: 88/209 - (42%)
• Similarity: 131/209 - (62%)
• Gaps: 27/209 - (12%)

  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFK----TGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTA 78
            :|.|||:::|||.|.||:.::.||.    :|:||    .||||||.::|:.:.|:::||||||||
Mouse     5 YDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYI----TTIGVDFKIRTVEINGEKVKLQIWDTA 65

  Fly    79 GQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQRE 143
            |||||||||.:|||..:||::|||:|...||.|:::|:.|:.: ...:|..||||||.|..|::.
Mouse    66 GQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQ-NCDDVCRILVGNKNDDPERKV 129

  Fly   144 VDFEEARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKR----------QHDANNVEEVPE 198
            |:.|:|.:....:...||  |||||||:|||:.|.|:...:.|          |...|:|.::.:
Mouse   130 VETEDAYKFAGQMGIQLF--ETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTK 192

  Fly   199 NTITLGQGKPLKSC 212
            |:      |..|.|
Mouse   193 NS------KRKKRC 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	80/168 (48%)
Rab35	NP_937806.1	Rab35	3..201	CDD:133310	88/209 (42%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q15286	30..42		4/15 (27%)
		Effector region. /evidence=ECO:0000250	37..45		6/11 (55%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q15286	64..80		13/15 (87%)