Protein Alignment Rab19 and Rab1b

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_083852.1
• Gene: Rab1b / 76308
• MGIID: 1923558
• Length: 201
• Species: Mus musculus
• Alignment Length: 216
• Identity: 96/216 - (44%)
• Similarity: 138/216 - (63%)
• Gaps: 21/216 - (9%)

  Fly     5 NPQTLMALPNEEHFDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQ 69
            ||:          :|:|||::||||.|.||:|::.||....|.|.:.:||||||.::||.::||.
Mouse     2 NPE----------YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT 56

  Fly    70 IKLQIWDTAGQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGN 134
            ||||||||||||||||||.||||.|:|:::|||:|.:.|::|:::|::|:.||.:.||..:||||
Mouse    57 IKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGN 121

  Fly   135 KCDLEEQREVDFEEARQMCQY--IPEILFVMETSAKENMNVEDAFRCLANELKRQ--HDANNVEE 195
            |.||..::.||...|::....  :|    .:|||||...|||.||..:|.|:|::  ..|.:..|
Mouse   122 KSDLTTKKVVDNTTAKEFADSLGVP----FLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGE 182

  Fly   196 VPENTITLGQGKPLKSCSSSC 216
            .|...|   ...|:|..|..|
Mouse   183 RPNLKI---DSTPVKPASGGC 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	84/166 (51%)
Rab1b	NP_083852.1	Rab1_Ypt1	7..172	CDD:206661	85/168 (51%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	30..45		6/14 (43%)
		Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250|UniProtKB:Q9H0U4	64..83		16/18 (89%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	65..80		13/14 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201		8/30 (27%)