Protein Alignment Rab19 and Rab2a

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_113906.2
• Gene: Rab2a / 65158
• RGDID: 68323
• Length: 212
• Species: Rattus norvegicus
• Alignment Length: 194
• Identity: 88/194 - (45%)
• Similarity: 128/194 - (65%)
• Gaps: 11/194 - (5%)

  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQER 82
            :.:|||.::|||.|.||:|::.:|....:...|..||||:|..:.|.::|||||||||||||||.
  Rat     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67

  Fly    83 FRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFE 147
            ||:||:||||.|.|.|:|||||:|.:|::|..|:|:.|:::.||::|:|:|||.|||.:|||..|
  Rat    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132

  Fly   148 EARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQ---------HDANNVEEVPENTIT 202
            |.....:  ...|..||||||...|||:||...|.|:..:         ::||.::..|::..|
  Rat   133 EGEAFAR--EHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAAT 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	83/164 (51%)
Rab2a	NP_113906.2	PLN03108	1..188	CDD:178655	86/186 (46%)
		Required for interaction with PRKCI. /evidence=ECO:0000250	2..19		7/15 (47%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..212		1/5 (20%)