Protein Alignment Rab19 and RAB27B

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_004154.2
• Gene: RAB27B / 5874
• HGNCID: 9767
• Length: 218
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 76/215 - (35%)
• Similarity: 120/215 - (55%)
• Gaps: 24/215 - (11%)

  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAV--------EGKQIK--L 72
            :|:|.|::.:||.|.|||..:.|:....:..:...|:|:||..|.:..        .||..|  |
Human     6 YDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHL 70

  Fly    73 QIWDTAGQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYT-ASNVLIILVGNKC 136
            |:||||||||||::|.:::|.|.|.|:::|:|.:.||.|::.|:.:::... ..|..|:|:|||.
Human    71 QLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKA 135

  Fly   137 DLEEQREVDFEEARQMC-QY-IPEILFVMETSAKENMNVEDAFRCLAN-ELKRQHDANNVEEVPE 198
            ||.:||||:..:||::. :| ||    ..||||....|||.|...|.: .:||........::|:
Human   136 DLPDQREVNERQARELADKYGIP----YFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTQIPD 196

  Fly   199 -----NTITL-GQGKPLKSC 212
                 |:..| |:..|.|.|
Human   197 TVNGGNSGNLDGEKPPEKKC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	67/178 (38%)
RAB27B	NP_004154.2	Rab27A	6..185	CDD:206700	68/182 (37%)
		Effector region. /evidence=ECO:0000250	38..46		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..218		7/23 (30%)