Protein Alignment Rab19 and RAB22A

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_065724.1
• Gene: RAB22A / 57403
• HGNCID: 9764
• Length: 194
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 76/201 - (37%)
• Similarity: 111/201 - (55%)
• Gaps: 25/201 - (12%)

  Fly    23 KIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRTIT 87
            |:.|:||.|.||:.||.||...::......|||..|..||:..:.:..|..|||||||||||.:.
Human     7 KVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALA 71

  Fly    88 QSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFEEARQM 152
            ..|||.:...:|||||||..:||.|:.|::|:|::...|:::.:.||||||.:.|||...:|:..
Human    72 PMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCDLIDVREVMERDAKDY 136

  Fly   153 CQYIPEILFVMETSAKENMNVEDAFRCLANELKRQ---HDANNVEEVPENTITLGQG-------- 206
            ...|..|.  :|||||..:|:.:.|    .|:.|:   .|||    :|..    |:|
Human   137 ADSIHAIF--VETSAKNAININELF----IEISRRIPSTDAN----LPSG----GKGFKLRRQPS 187

  Fly   207 KPLKSC 212
            :|.:||
Human   188 EPKRSC 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	65/160 (41%)
RAB22A	NP_065724.1	Rab5_related	5..167	CDD:206653	67/165 (41%)
		Effector region. /evidence=ECO:0000250	34..42		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..194		6/24 (25%)