Protein Alignment Rab19 and Rab25

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_058595.2
• Gene: Rab25 / 53868
• MGIID: 1858203
• Length: 213
• Species: Mus musculus
• Alignment Length: 195
• Identity: 76/195 - (38%)
• Similarity: 122/195 - (62%)
• Gaps: 6/195 - (3%)

  Fly    15 EEHFDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAG 79
            :|.::|:||:||||:.|.|||.::.||....:......||||:||.:|:.:....:|.|||||||
Mouse     6 DEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAG 70

  Fly    80 QERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREV 144
            .||:|.||.:|||.|.|.|:|:|:||..:::.:::|::|:..:..:.::::|||||.||.:.|||
Mouse    71 LERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREV 135

  Fly   145 DFEEARQMCQYIPE--ILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGK 207
            ..|||   |.:...  :|| :||||.::.|||.||:.:..|:..:...........:.||||..:
Mouse   136 PTEEA---CMFAENNGLLF-LETSALDSTNVELAFQTVLKEIFAKVSKQKQNSTRTSAITLGNAQ 196

  Fly   208  207
            Mouse   197  196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	70/166 (42%)
Rab25	NP_058595.2	Rab11_like	11..174	CDD:206660	71/166 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	35..49		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	67..84		11/16 (69%)