DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab19 and RAB8B

DIOPT Version :9

Sequence 1:NP_001261575.1 Gene:Rab19 / 38930 FlyBaseID:FBgn0015793 Length:219 Species:Drosophila melanogaster
Sequence 2:NP_057614.1 Gene:RAB8B / 51762 HGNCID:30273 Length:207 Species:Homo sapiens


Alignment Length:198 Identity:86/198 - (43%)
Similarity:131/198 - (66%) Gaps:17/198 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQER 82
            :|:|||::||||.|.||||::.||....:.....:|||:||.::||.::||:|||||||||||||
Human     5 YDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69

  Fly    83 FRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFE 147
            |||||.:|||.|.|:::|||||...||.|::.||..:..:.:|:|..:::|||||:.::|:|..|
Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKE 134

  Fly   148 EARQMCQYIPEILFVMETSAKENMNVEDAFRCLANEL-----KRQHDANNVEEVPENTITLGQGK 207
            ...::.  |...:..:|||||.:.|||:||..||.::     ::.:|:|:.          |.|.
Human   135 RGEKLA--IDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSA----------GAGG 187

  Fly   208 PLK 210
            |:|
Human   188 PVK 190

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab19NP_001261575.1 Rab19 19..184 CDD:133267 80/164 (49%)
RAB8BNP_057614.1 Rab8_Rab10_Rab13_like 6..172 CDD:206659 80/167 (48%)
Effector region. /evidence=ECO:0000250 37..45 3/7 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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