Protein Alignment Rab19 and RAB6B

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_057661.3
• Gene: RAB6B / 51560
• HGNCID: 14902
• Length: 208
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 79/199 - (39%)
• Similarity: 121/199 - (60%)
• Gaps: 8/199 - (4%)

  Fly    22 FKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRTI 86
            ||:|.:|:...|||.::.||...::...:..|||:||..||:.:|.:.::||:||||||||||::
Human    14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 78

  Fly    87 TQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFEEARQ 151
            ..||.|.:...::|||||..:||....|||::||....|:|:|:|||||.||.::|::..||..|
Human    79 IPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQ 143

  Fly   152 MCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGKPLKSCSS-- 214
            ..:.: .::|: |||||...||:..||.:|:.|....  |..|:..|..|.:...||.:..:|
Human   144 RAKEL-SVMFI-ETSAKTGYNVKQLFRRVASALPGME--NVQEKSKEGMIDIKLDKPQEPPASEG 204

  Fly   215 --SC 216
              ||
Human   205 GCSC 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	69/161 (43%)
RAB6B	NP_057661.3	Rab6	14..174	CDD:206654	69/161 (43%)
		Switch 1. /evidence=ECO:0000269|PubMed:16790928, ECO:0007744|PDB:2FE4, ECO:0007744|PDB:2FFQ	39..49		3/9 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:16790928, ECO:0007744|PDB:2FE4, ECO:0007744|PDB:2FFQ	71..87		9/15 (60%)