Protein Alignment Rab19 and RAB14

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_057406.2
• Gene: RAB14 / 51552
• HGNCID: 16524
• Length: 215
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 88/200 - (44%)
• Similarity: 128/200 - (64%)
• Gaps: 7/200 - (3%)

  Fly    17 HFDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQE 81
            ::.::||.::|||.|.||:|::.:|....::....:||||:|..:.|.|.|::||||||||||||
Human     7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQE 71

  Fly    82 RFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDF 146
            |||.:|:||||.|.|.|:|||||:||::::|..|:.:.|..|..|.:|||:|||.|||.||:|.:
Human    72 RFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTY 136

  Fly   147 EEARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKR-----QHDANNVEEVPENTITLGQG 206
            |||:|..:  ...|..:|.|||...||||||...|.::.:     ..|.|..|...::..:..||
Human   137 EEAKQFAE--ENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQG 199

  Fly   207 KPLKS 211
            ..|.|
Human   200 GRLTS 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	81/164 (49%)
RAB14	NP_057406.2	Rab14	10..175	CDD:133322	81/166 (49%)
		Switch 1. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	42..47		3/4 (75%)
		Switch 2. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	68..77		7/8 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..215		3/16 (19%)