Protein Alignment Rab19 and RAB8A

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 87/195 - (44%)
• Similarity: 130/195 - (66%)
• Gaps: 7/195 - (3%)

  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQER 82
            :|:|||::||||.|.||||::.||....:.....:|||:||.::||.::||:|||||||||||||
Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69

  Fly    83 FRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFE 147
            |||||.:|||.|.|:::|||||...||.|::.||..:..:.:::|..:::|||||:.::|:|..|
Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134

  Fly   148 EARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENT-----ITLGQGK 207
            ...::.  :...:..||||||.|:|||:||..||.::|.:.|.......|:.:     ||..|.|
Human   135 RGEKLA--LDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQK 197

  Fly   208  207
            Human   198  197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	80/164 (49%)
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	81/167 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		3/13 (23%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		14/16 (88%)