DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab19 and rab-10

DIOPT Version :9

Sequence 1:	NP_001261575.1	Gene:	Rab19 / 38930	FlyBaseID:	FBgn0015793	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_491857.1	Gene:	rab-10 / 266836	WormBaseID:	WBGene00004273	Length:	201	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	89/217 - (41%)
Similarity:	131/217 - (60%)	Gaps:	26/217 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ARNPQTLMALPNEEHFDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEG 67
            ||.|           :|.|||::||||.|.|||||:.||....:.....:|||:||.:|||.::|
Worm     2 ARRP-----------YDMLFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKG 55

  Fly    68 KQIKLQIWDTAGQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILV 132
            |:||||||||||||||.|||.||||.|.|:::|||||...||.|:.||:..:..:.:.:|:.:::
Worm    56 KKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHASEDVVKMIL 120

  Fly   133 GNKCDLEEQREVDFEEARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVP 197
            |||||:.::|.|..|...::.|  ...:...|||||.|::|:.||..||..:        :.::|
Worm   121 GNKCDMSDRRVVSRERGEKIAQ--DHGISFHETSAKLNVHVDTAFYDLAEAI--------LAKMP 175

  Fly   198 ENT-----ITLGQGKPLKSCSS 214
            ::|     .|:...:|.:..||
Worm   176 DSTDEQSRDTVNPVQPQRQSSS 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_001261575.1	Rab19	19..184	CDD:133267	80/164 (49%)
rab-10	NP_491857.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	80/175 (46%)
rab-10	NP_491857.1	RAB	10..173	CDD:197555	78/172 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910