Protein Alignment Rab19 and RAB18

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 83/235 - (35%)
• Similarity: 119/235 - (50%)
• Gaps: 49/235 - (20%)

  Fly    23 KIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIW------------ 75
            ||::||:.|.||:.::.||....:......||||||.:|||:|:|.:.||.||
Human    10 KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTLHQQTANFFL 74

  Fly    76 -----------------DTAGQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRY- 122
                             ||||||||||:|.||||.|.||::|||:|:|.:|..|..|:.|:..|
Human    75 KSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYC 139

  Fly   123 TASNVLIILVGNKCDLEEQREVDFEEARQMCQYIPEILFVMETSAKENMNVEDAFRCLAN----- 182
            |.::::.:|||||.| :|.||||..|..:..:. ..:||: |.|||....|:.||..|..
Human   140 TRNDIVNMLVGNKID-KENREVDRNEGLKFARK-HSMLFI-EASAKTCDGVQCAFEELVEKIIQT 201

  Fly   183 ----ELKRQHDANNVEEVPENTITLGQGKPLKSCSSSCNL 218
                |.:.|:....:....|     |||.  .:|...|::
Human   202 PGLWESENQNKGVKLSHREE-----GQGG--GACGGYCSV 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	75/199 (38%)
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	75/190 (39%)