Protein Alignment Rab19 and Rab17

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_033024.1
• Gene: Rab17 / 19329
• MGIID: 104640
• Length: 214
• Species: Mus musculus
• Alignment Length: 196
• Identity: 70/196 - (35%)
• Similarity: 114/196 - (58%)
• Gaps: 11/196 - (5%)

  Fly    20 FLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGN---TIGVDFSMKTIAVEGKQIKLQIWDTAGQE 81
            ::.|:||:|....|||.:..|:...::    .|   |:|..|..|.:.:....:||:||||||||
Mouse    18 YVSKLVLLGSSSVGKTSLALRYMKQDF----SNVLPTVGCAFFTKVLDLGSSSLKLEIWDTAGQE 78

  Fly    82 RFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEV-RRYTASNVLIILVGNKCDLEEQREVD 145
            :::::...|:|.||..|:|||||::.||...|:|:|:: :.:....|:::|||||.||.|:|||.
Mouse    79 KYQSVCHLYFRGANAALLVYDITRKDSFHKAQQWLEDLEKEFQPGEVVVMLVGNKTDLGEEREVT 143

  Fly   146 FEEARQMCQYIPEILFVMETSAKENMNVEDAFRCLANE-LKRQHDANNVEEVPENTITLGQGKPL 209
            |:|.::..:  .:.|..||||||.|..|.:.|..:|.| |:|..|..:........:.|.|..|:
Mouse   144 FQEGKEFAE--SKSLLFMETSAKLNYQVSEIFNTVAQELLQRAGDTGSSRPQEGEAVALNQEPPI 206

  Fly   210 K 210
            :
Mouse   207 R 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	64/168 (38%)
Rab17	NP_033024.1	Rab5_related	21..181	CDD:206653	64/165 (39%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	43..54		3/14 (21%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	75..91		6/15 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..204		4/20 (20%)