DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab19 and rab-8

DIOPT Version :9

Sequence 1:	NP_001261575.1	Gene:	Rab19 / 38930	FlyBaseID:	FBgn0015793	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_491199.2	Gene:	rab-8 / 171935	WormBaseID:	WBGene00004272	Length:	211	Species:	Caenorhabditis elegans

Alignment Length:	209	Identity:	97/209 - (46%)
Similarity:	140/209 - (66%)	Gaps:	11/209 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQER 82
            :|:|||::||||.|.||||::.||...::.....:|||:||.::||.::||:|||||||||||||
Worm     5 YDYLFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69

  Fly    83 FRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFE 147
            |||||.:|||.|.|:::|||||...||.|::.||..:..:.||:|..:::|||||:||:|||..:
Worm    70 FRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCDIEERREVSRD 134

  Fly   148 EARQMC-QYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEE--VPENTITL---GQG 206
            ...|:. :|..:.|   |||||.|:|:::||..||.::|.:.:.|.:..  ...||..:   |.|
Worm   135 RGEQLAIEYGTKFL---ETSAKANLNIDEAFFTLARDIKSKMEQNEMRAGGSVSNTGRVNVGGSG 196

  Fly   207 KPLKSCSS--SCNL 218
            ...||..|  ||||
Worm   197 TQKKSFFSNWSCNL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_001261575.1	Rab19	19..184	CDD:133267	84/165 (51%)
rab-8	NP_491199.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	85/168 (51%)
rab-8	NP_491199.2	RAB	9..172	CDD:197555	83/165 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910