Protein Alignment Rab19 and RAB31

DIOPT Version :10

• Sequence 1: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_006859.2
• Gene: RAB31 / 11031
• HGNCID: 9771
• Length: 195
• Species: Homo sapiens
• Alignment Length: 194
• Identity: 73/194 - (37%)
• Similarity: 111/194 - (57%)
• Gaps: 7/194 - (3%)

  Fly    23 KIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRTIT 87
            |:.|:||.|.||:.||.||...::......|||..|..||:....:..|..||||||||||.::.
Human     8 KVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLA 72

  Fly    88 QSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFEEARQM 152
            ..|||.:...:|||||||:.||..|:||::|::.:...|:::.:.||||||.:.|||..::|::.
Human    73 PMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEY 137

  Fly   153 CQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGKPLKSCSSSC 216
            .:.|..|  |:|||||..:|:|:.|:.::.::.......|     .|..|:...||....|..|
Human   138 AESIGAI--VVETSAKNAINIEELFQGISRQIPPLDPHEN-----GNNGTIKVEKPTMQASRRC 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	66/160 (41%)
RAB31	NP_006859.2	Rab5_related	6..168	CDD:206653	66/161 (41%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	30..42		3/11 (27%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	63..79		9/15 (60%)