DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab19 and RAB10

DIOPT Version :9

Sequence 1:	NP_001261575.1	Gene:	Rab19 / 38930	FlyBaseID:	FBgn0015793	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_057215.3	Gene:	RAB10 / 10890	HGNCID:	9759	Length:	200	Species:	Homo sapiens

Alignment Length:	199	Identity:	85/199 - (42%)
Similarity:	125/199 - (62%)	Gaps:	5/199 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQER 82
            :|.|||::||||.|.||||::.||....:.....:|||:||.:||:.::||:|||||||||||||
Human     6 YDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70

  Fly    83 FRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFE 147
            |.|||.||||.|.|:::|||||...||.|:.||:..:..:...:|..:|:|||||::::|.|...
Human    71 FHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKG 135

  Fly   148 EARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGKPLKSC 212
            :..|:.:  ...:...|||||.|:|:|.||..||.::.|:   ..|:|.....:.:..|..:...
Human   136 KGEQIAR--EHGIRFFETSAKANINIEKAFLTLAEDILRK---TPVKEPNSENVDISSGGGVTGW 195

  Fly   213 SSSC 216
            .|.|
Human   196 KSKC 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab19	NP_001261575.1	Rab19	19..184	CDD:133267	79/164 (48%)
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	79/167 (47%)
RAB10	NP_057215.3	Effector region. /evidence=ECO:0000250	38..46		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910