DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cert and PCTP

DIOPT Version :9

Sequence 1:	NP_001286978.1	Gene:	cert / 38928	FlyBaseID:	FBgn0027569	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001317307.1	Gene:	PCTP / 58488	HGNCID:	8752	Length:	219	Species:	Homo sapiens

Alignment Length:	252	Identity:	49/252 - (19%)
Similarity:	98/252 - (38%)	Gaps:	55/252 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 VAEGEEAREEFGTGAEATSHALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEE 409
            :|.|..:.|:|           |    ..|.|....|..|.     .||:..:...|.:|:..::
Human     3 LAAGSFSEEQF-----------W----EACAELQQPALAGA-----DWQLLVETSGISIYRLLDK 47

  Fly   410 VNGLVMDPLKAYHTVQGVTAREMCHYFFMPEFRNDWETTLEDCTILEKISADTLLFLQTHKRIWP 474
            ..||.  ..|.:..::..:...:...:...::|..|:..::: ...::.:.:|:::.:. |..:|
Human    48 KTGLY--EYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKE-LYEQECNGETVVYWEV-KYPFP 108

  Fly   475 ASQRDAQFWSHMRKITDNLEPGARDMWVVCNNSTEYAKQESKNGKCVRI-FLTVILACQTHLPEG 538
            .|.||   :.::|:..| |:...|.:.|:...||...:...::| .:|: .....||.::...:|
Human   109 MSNRD---YVYLRQRRD-LDMEGRKIHVILARSTSMPQLGERSG-VIRVKQYKQSLAIESDGKKG 168

  Fly   539 YVKGQPLNRNDLTCKITYCSVVNPGG--------WAPASALR----AVYKREYPKFL 583
                         .|:......||||        ||..:..|    |..:|:..|||
Human   169 -------------SKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQNQRDLIKFL 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594
		PH_GPBP	42..142	CDD:270100
		START_STARD11-like	363..601	CDD:176881	45/234 (19%)
PCTP	NP_001317307.1	START_STARD2-like	4..194	CDD:176919	43/231 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910