Protein Alignment cert and Plekha8

DIOPT Version :9

• Sequence 1: NP_001286978.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001102705.1
• Gene: Plekha8 / 500132
• RGDID: 1563940
• Length: 520
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 130/595 - (21%)
• Similarity: 210/595 - (35%)
• Gaps: 205/595 - (34%)

  Fly    42 LRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVV 106
            :.|.|.|||||:.|||||:.:|..|.||||.|..::..||:|:|.:....|:.|..|..|.|:::
  Rat     1 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLII 65

  Fly   107 NNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQR 171
            .....:.|:|.:..:|..|  ::.|..|.:..||:    |.........||             .
  Rat    66 PGEQYFYLKARSVAERQRW--LVALGSAKACLTDS----RTQKEKEFAENT-------------E 111

  Fly   172 NLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTSG 236
            ||:.|:.||..:.|:|..|::..:....|            .:.|..:.||.   ....|:|.:.
  Rat   112 NLKTKMSELRLYCDLLVQQVDKTKEVATA------------GVADSEEGIDV---GTLLRSTCNT 161

  Fly   237 VLTTLQHCLEI--IAESDE----------------SWKRK---------LEREID---------- 264
            .|.||:.|::|  .|.:.|                |.|.|         |||.|:
  Rat   162 FLKTLEECMQIANAAFTSELLYHTPPGSPQLAVLKSSKMKHPIIPIHNSLERPIELNSCENGSLS 226

  Fly   265 -----------KRRRSEDQSKKLKDEV----------------EKMKR------------LSYPG 290
                       |.::|....|..|.:.                |:||.            |:.||
  Rat   227 VEVNGDEELLMKTKKSSLYLKSTKADCNISSEENTDGNTTVQGERMKEDGEENLESHDRDLAQPG 291

  Fly   291 PDFEEGPHSTLPEDE-----FFDAVETGLDKIE--EDMQLRFKLKLQSQISQTLVNVPHEAVAEG 348
            .|....|.|...:.|     ||..:.|....||  ||.                 .:|.||..
  Rat   292 SDSVCSPESPWEDSEEVIPTFFSTMNTSFSDIELLEDS-----------------GIPTEAFL-- 337

  Fly   349 EEAREEFGTGAEATSHALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEEVNGL 413
                        |:.:|:.|.:|::                 |..:||   .:||     ::.|.
  Rat   338 ------------ASCYAVVPVLDKL-----------------GPTVFA---PVKM-----DLVGN 365

  Fly   414 VMDPLKAYHTVQGVTAREMCHYFFMPEFRNDWETTLEDCTILEKISADTLLFLQ--THKRIWPAS 476
            :....:.|     :|.:|        ||     |||:. .:|.::.||......  |...:|  .
  Rat   366 IKKVNQKY-----ITNKE--------EF-----TTLQK-IVLHEVEADVARVRNSATEALLW--L 409

  Fly   477 QRDAQFWSHMRKITDNLEPGARDMWVVCNNSTEYAKQ-ESKNGKCVR-IFLTVILACQTHLPEGY 539
            :|..:|   ::.....::.|.:|:....||:  |.|. ...:|..|| :|...:.|..::  |.:
  Rat   410 KRGLKF---LKGFLTEVKNGEKDIQTALNNA--YGKTLRQHHGWVVRGVFALALRAAPSY--EDF 467

  Fly   540 VKGQPLNRND 549
            |....:...|
  Rat   468 VAALTIKEGD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	32/87 (37%)
		PH_GPBP	42..142	CDD:270100	36/99 (36%)
		START_STARD11-like	363..601	CDD:176881	38/191 (20%)
Plekha8	NP_001102705.1	PH_FAPP1_FAPP2	1..100	CDD:269951	36/104 (35%)
		PH	1..93	CDD:278594	34/93 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..303		9/47 (19%)
		Glycolipid transfer protein homology domain	311..520		49/251 (20%)
		GLTP	334..471	CDD:285880	40/203 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910