Protein Alignment cert and plekha8

DIOPT Version :9

• Sequence 1: NP_001286978.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001007375.1
• Gene: plekha8 / 492502
• ZFINID: ZDB-GENE-041114-69
• Length: 549
• Species: Danio rerio
• Alignment Length: 590
• Identity: 133/590 - (22%)
• Similarity: 233/590 - (39%)
• Gaps: 115/590 - (19%)

  Fly    42 LRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVV 106
            :.|.|.||||||.|||||:.||:.||||||.|:.::..||:|:|.::...|:.|.||..|.|:::
Zfish     1 MEGVLYKWTNYISGWQPRWFVLEGGTLSYYDSQEDAWKGCKGSIKISVCEIQVHPSDFTRVDLII 65

  Fly   107 NNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQR 171
            .....:.|||..:.:|..|:..|...||  ..||..:.|.    ..||.|:             .
Zfish    66 PGEQYFYLRAINAAERQKWLVALGTAKA--CLTDNRTKRE----KELQENS-------------E 111

  Fly   172 NLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTSG 236
            .|:.|:.||..:.|:|..|:..:|.     |.:.:.:|...:.||...::        .::|.:.
Zfish   112 ALKTKMSELRLYCDLLLQQVNKIQE-----SPLAETSAGSGEGGDETGNL--------VKSTCTT 163

  Fly   237 VLTTLQHCLEIIAE---------------SDESWKRKLEREIDKRRRSEDQSKKLKDEVEKMKRL 286
            .|.||:.|:.|.:.               |..:.|.:..:..|.:.....:::  ||.:......
Zfish   164 FLKTLEECMHIASRTFNPDLLSRTPPGSPSVATIKPQKIKSNDPKNLHPGETR--KDLINTSGTS 226

  Fly   287 SY-PGPDFEEGPHSTLPEDEFFDA-VETGLDKIEEDMQLRFKLKLQSQISQTLVNVPHEAVAEGE 349
            :: .|||.|..|.   |::....| .|:||.:.:.|:       ::.....:.....||   |..
Zfish   227 AHESGPDNEPPPS---PQENISTAHTESGLMEDQNDL-------IEPNNGSSSSTQDHE---EPV 278

  Fly   350 EAREEFGTGAEAT-SHALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEEVNGL 413
            |.::..|:..:|. |.....|:.....:.....:|.:..|   .::...:.|.|..:.:|
Zfish   279 EEQQTDGSTEDADHSQEEQQEVSMSPTQNKQEVQEDIQTD---LELNETQSENKQEEEDE----- 335

  Fly   414 VMDPLKAYHTVQGVTAREMCHYFFMPEFRND----WETTLEDC----TILEKISADTLL-----F 465
              |.:..:.:.       |.|.|.......|    .:..|:.|    .:|:|:......     |
Zfish   336 --DKVDTFFST-------MSHRFSDIILEEDSGIPTQAFLDSCYAIVPVLDKLGPTVFAPVKIDF 391

  Fly   466 LQTHKRIWPASQRDAQFWSHMRKITDNLEPGARDMWVVCNNSTEYAKQESKNGKCVRIFLTVILA 530
            :...|:|......|.:.:..::.|.  |.....::..|.|::||......:..|.::.||:.|
Zfish   392 VGNIKKIQQKVVSDPESFPTLQSIV--LHEVKTEVAQVRNSATEALLWLKRGLKFLKEFLSEI-- 452

  Fly   531 CQTHLPEGYVKGQPLNRNDLTCKITYCSVVNPGGWAP----ASALRAVYKREYPKFLKRFTGYVI 591
             .|.:.:  |:|...|....|.:..:       ||..    |.||||.  ..|..|:.....|..
Zfish   453 -NTGVKD--VQGALYNAYGKTLRQYH-------GWVVRGVFALALRAA--PSYEGFMAALVSYEG 505

  Fly   592 DQCKD 596
            |:.|:
Zfish   506 DELKE 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	37/87 (43%)
		PH_GPBP	42..142	CDD:270100	42/99 (42%)
		START_STARD11-like	363..601	CDD:176881	47/251 (19%)
plekha8	NP_001007375.1	PH_FAPP1_FAPP2	1..100	CDD:269951	42/100 (42%)
		PH	1..88	CDD:278594	37/86 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..312		24/146 (16%)
		GLTP	363..500	CDD:285880	32/152 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910