Protein Alignment cert and Osbp

DIOPT Version :10

• Sequence 1: NP_648199.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 125/551 - (22%)
• Similarity: 207/551 - (37%)
• Gaps: 110/551 - (19%)

  Fly    41 ELRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVV 105
            |::|:|.||||||.|:|.|:.||..|.||||:::||.:..|||.|||..|.|  |..|...|.:.
  Fly    16 EMKGWLLKWTNYIKGYQRRWFVLSKGVLSYYRNQSEINHTCRGTISLHGALI--HTVDSCTFVIS 78

  Fly   106 VNNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQ 170
            ......:.::|.|..:|..||..|:|.||       .::|........::.|..:.....:....
  Fly    79 NGGTQTFHIKAGTEVERQSWVTALELAKA-------KAIRAIECEEEEETETAHVVPSQEISSVV 136

  Fly   171 RNLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTS 235
            |:|.:::..:.|..|::......|||   |.:::..|..:  .||...|.::.:  :..||.|::
  Fly   137 RDLTDRLESMRTCYDLITKHGAALQR---ALNDLETNEEE--SLGSRTKIVNER--ATLFRITSN 194

  Fly   236 GVLTTLQHCLEIIAESDESWKRKLEREIDKRRRSE---DQSKKLKDEVEKM-------KRLSYPG 290
            .::......|.........|.:.|..|.::|:|.|   :|..|.:.::|:.       |.:|...
  Fly   195 AMINAGNDYLHTAEAQGHKWSKMLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVRQNKPVSSTS 259

  Fly   291 PDFEEGPHSTLPED-EFFDAVE---TGLDKIEEDMQLR---FKLKLQSQISQTLVNVPHEAVAEG 348
            .....|...|..|: |||||.|   :|..:..|.....   |.||:..:.|.:...|........
  Fly   260 GAGTAGSLVTSDEEMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSEDQVEGHLEGSS 324

  Fly   349 EEAREEFGTGAEATSHALWPEIDRVCKEQL-HYAREGVGQD------------------GNGWQI 394
            .|:.|:..|         ...:.:||.... ..|..|.|.|                  |..|
  Fly   325 SESDEQKRT---------VQTVQQVCLVSAPRVASGGQGDDDDDVDKALPAKESTDSIYGRNW-- 378

  Fly   395 FADEGEIKMYKREEEVNGLVMDPLKAYHTVQGVTAREMCHYFFMPEFR----------NDWE--- 446
              :...||  ||.:.|......|:..:..::....:::........|.          .|:|
  Fly   379 --NPDLIK--KRRDRVPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTE 439

  Fly   447 ------TTLEDCTILEKISADTL-LFLQTHKR-----------IWPASQRDAQFWSHMRKITDNL 493
                  |..::|..|..|:|.|: .:..|..|           .:...:.|...|..:.:...:.
  Fly   440 ILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHH 504

  Fly   494 EPGARDMWVVCNNSTEYAKQESKNGKCVRIF 524
            .|.|.   :.|         ||||..|.:.|
  Fly   505 PPVAA---LHC---------ESKNWTCWQEF 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_648199.1	PH_GPBP	42..142	CDD:270100	40/99 (40%)
		START_STARD11-like	363..601	CDD:176881	36/212 (17%)
Osbp	NP_477271.1	PH_OSBP_ORP4	17..113	CDD:270101	41/104 (39%)
		Oxysterol_BP	399..773	CDD:460126	22/137 (16%)