Protein Alignment cert and Plekha8

DIOPT Version :9

• Sequence 1: NP_001286978.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001157833.1
• Gene: Plekha8 / 231999
• MGIID: 2681164
• Length: 519
• Species: Mus musculus
• Alignment Length: 597
• Identity: 133/597 - (22%)
• Similarity: 211/597 - (35%)
• Gaps: 177/597 - (29%)

  Fly    42 LRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVV 106
            :.|.|.|||||:.|||||:.:|..|.||||.|..::..||:|:|.:....|:.|..|..|.|:::
Mouse     1 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLII 65

  Fly   107 NNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQR 171
            .....:.|:|.:..:|..|  ::.|..|.:..||:    |.........||             .
Mouse    66 PGEQYFYLKARSVAERQRW--LVALGSAKACLTDS----RTQKEKEFAENT-------------E 111

  Fly   172 NLREKVGELETFKDILFGQIETLQRYFDACSEVN----KNNAQPLDLGDGLKSIDFKGESITFRA 232
            ||:.|:.||..:.|:|..|:       |...||.    .::.:.:|:|..|||
Mouse   112 NLKTKMSELRLYCDLLVQQV-------DKTKEVATAGVTDSEEGIDVGTLLKS------------ 157

  Fly   233 TTSGVLTTLQHCLEIIAESDESWKRKLEREIDKRRRSEDQSKKLKDEVEKMKRLSYPGPDFEEGP 297
            |.:..|.||:.|::|   ::.::..:|   :........|...||.  .|||....|       .
Mouse   158 TCNTFLKTLEECMQI---ANAAFTSEL---LYHTPPGSPQLAVLKS--SKMKHPIIP-------I 207

  Fly   298 HSTLPEDEFFDAVETGLDKIE--EDMQLRFKLKLQSQISQTLV--------NVPHEAVAEGEEAR 352
            |::|......::.|.|...||  .|.::..|.|....:..|.|        |.......:||..:
Mouse   208 HNSLERSMELNSCENGSLSIEVNGDEEILMKTKSSLYLKSTEVDCSISSEENTDDNVTVQGEIMK 272

  Fly   353 EEFGTGAEATSH---ALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEEVNGLV 414
            |:.....|  ||   ...|..|.||..:            :.|:            ..|||
Mouse   273 EDGEENLE--SHDKDPAQPGSDSVCSPE------------SPWE------------DNEEV---- 307

  Fly   415 MDPLKAYHTVQGVTAREMCHYFFMPEFRNDWETTLEDCTILEKISADTLLFLQTHKRIWPASQR- 478
                                   :|.|.:...|:..|..:||.....|..||.:...:.|...:
Mouse   308 -----------------------IPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKL 349

  Fly   479 -------------------------DAQFWSHMRKITDNLEPGARDMWVVCNNSTEYAKQESKNG 518
                                     :.:.::.::||.  |.....|:..|.|::||......:..
Mouse   350 GPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIV--LHEVEADVAQVRNSATEALLWLKRGL 412

  Fly   519 KCVRIFLTVI----LACQTHLPEGYVKGQPLNRNDLTCKITYCSVVNPGGWAP----ASALRAVY 575
            |.::.|||.:    ...||.|...|  |:.|.::.              ||..    |.||||.
Mouse   413 KFLKGFLTEVKNGEKDIQTALNNAY--GKTLRQHH--------------GWVVRGVFALALRAA- 460

  Fly   576 KREYPKFLKRFT 587
             ..|..|:...|
Mouse   461 -PSYEDFVAALT 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	32/87 (37%)
		PH_GPBP	42..142	CDD:270100	36/99 (36%)
		START_STARD11-like	363..601	CDD:176881	48/262 (18%)
Plekha8	NP_001157833.1	PH_FAPP1_FAPP2	1..100	CDD:269951	36/104 (35%)
		PH	1..93	CDD:278594	34/93 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	275..302		7/40 (18%)
		Glycolipid transfer protein homology domain	330..473		32/162 (20%)
		GLTP	333..470	CDD:285880	30/156 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910