DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cert and obr-2

DIOPT Version :9

Sequence 1:	NP_001286978.1	Gene:	cert / 38928	FlyBaseID:	FBgn0027569	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_506695.2	Gene:	obr-2 / 180003	WormBaseID:	WBGene00008832	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	46/255 - (18%)
Similarity:	81/255 - (31%)	Gaps:	55/255 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 KLEREIDKRRRSEDQSKKLKDEVEKMKRLSYP-------------------GPDFEEGPHSTLPE 303
            ||.||.......:.|:.|.:..:.|.:|...|                   |.||.   ..|:|
Worm     3 KLFREKKDMGSPKIQNFKRQTVLHKGQRTRLPATYIAPEDVSIWDIIRPNLGKDFS---RFTVP- 63

  Fly   304 DEFFDAVETGLDKIEEDMQLRFKLKLQSQISQTLVNVPHEAVAEGEEAREEFGTGAEATSH---- 364
             .|.:...:.|.::.|::|..:.|:..::.|..:..:.:.|.         |.....:.:|
Worm    64 -VFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEYVAA---------FALATVSANHKRLS 118

  Fly   365 ----ALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEEVNGLVMDPLKAYHTVQ 425
                .|..|...:.:..:.:..|.|........::|:..|..:....|...|..|..|.|..
Worm   119 KPFNPLLLETFELERNGVRFLAEQVSHHPPISAVYAESDEFTVEGTVEPTLGFWMTKLLANP--- 180

  Fly   426 GVTAREMCHYFFMPEFRNDWET---TLEDCTILEKISADTLLFLQTHKRIWPASQRDAQF 482
                    |......|:...||   :...|.|...|.....:...:|.:|..:...||.|
Worm   181 --------HAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMKIESSGTYDAVF 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594
		PH_GPBP	42..142	CDD:270100
		START_STARD11-like	363..601	CDD:176881	24/131 (18%)
obr-2	NP_506695.2	Oxysterol_BP	44..401	CDD:279564	37/214 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910