Protein Alignment cert and F25H2.6

DIOPT Version :9

• Sequence 1: NP_001286978.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_492762.1
• Gene: F25H2.6 / 172940
• WormBaseID: WBGene00009120
• Length: 573
• Species: Caenorhabditis elegans
• Alignment Length: 589
• Identity: 187/589 - (31%)
• Similarity: 302/589 - (51%)
• Gaps: 61/589 - (10%)

  Fly    44 GYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVVNN 108
            |.:.|||||:.|||.||..:.:|.|.||.|::|...||||:|.|..|.|.|||.||..|.:.:..
 Worm    11 GVMKKWTNYVNGWQDRYFEITEGNLVYYLSKAEKSHGCRGSIFLKSAIIAAHEFDENEFSISMGE 75

  Fly   109 LNNWCLRAETSEDRMHWV-----DVLQLYKADSGSTDTTSLRRHGSTMS-LQSNTISLTSGGSLK 167
            ...|.|:||.|:.::.|:     :.:| ..:|..||.|.|..|:.|..| |.:|........|.|
 Worm    76 NVVWYLKAENSQSKLLWMRSVVRETVQ-NDSDYSSTSTKSHSRNPSVSSVLATNNQKSDDNESTK 139

  Fly   168 KTQRNLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRA 232
            .    ...|:.|||.::.:...|:.:::|.              |:.| |...|..:...::.:|
 Worm   140 L----FATKLSELEAYRTMCKDQMTSIERL--------------LEQG-GASCIVPQATILSVKA 185

  Fly   233 TTSGVLTTLQHCLEII--------------AESDESWKRKL--EREIDK---RRRSEDQSKKLKD 278
            |...::..:.|.::::              :.:...::..|  .|.:..   ||.|..:.:.:.|
 Worm   186 THLALIVNINHIVDLVKTSKVVIPNIPSSSSSTPPPFREPLCATRSVSSSVLRRESIVEQEYMSD 250

  Fly   279 EVEKMKRLS-YPGPDFEEGPHSTLPEDEFFDAVETGLDKIEEDMQLRFKLKLQSQISQTLVNVPH 342
            :...|...: ...||.:    .|...||||||.|..:|....|...:.:.:::.:.:..:| ||.
 Worm   251 DNSTMTTSTIIARPDID----VTSDCDEFFDADEFDVDSKNGDTVEKRQEEVEDKKNGNIV-VPE 310

  Fly   343 EAV------AEGEEAREEFGTGAEATSHALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEI 401
            |..      .||......:.....:..|:|:..||::..|||.||.  .|.:.|.|.:||::|.:
 Worm   311 EEKKKTSFRIEGNPVTGHYDDLLVSQEHSLYTTIDKLALEQLKYAL--AGAEDNVWSLFAEDGPM 373

  Fly   402 KMYKRE-EEVNGLVMDPLKAYHTVQGVTAREMCHYFFMPEFRNDWETTLEDCTILEKISADTLLF 465
            :||.|: |:..|:.:|||||.|.|.||||.|..|||:...::..|:.|||..:::|.||.|:::.
 Worm   374 RMYTRQIEDEGGVPVDPLKAIHAVDGVTALEFMHYFYDARYKMQWDHTLEAMSVVEHISPDSVVL 438

  Fly   466 LQTHKRIWPASQRDAQFWSHMRKITDNLEPGARDMWVVCNNSTEYAKQESKNGKCVRIFLTVILA 530
            .|.||.:|||:.|::.|.||:|::.::...||.|:::|||...:.|.....:...||:.|||.:.
 Worm   439 HQKHKTVWPAAPRESLFVSHIRRVDEHKRDGAHDLYIVCNRDIQRADVPLGSSSSVRVGLTVSMI 503

  Fly   531 CQTHLPEGYVKGQPLNRNDLTCKITYCSVVNPGGWAPASALRAVYKREYPKFLKRFTGYVIDQCK 595
            |:|.:.:.:: .:.|.|:|:.|.|.|.|.|:||||.|.:|||.|||:||||||:.||.:|....|
 Worm   504 CETTVKDPHI-DRKLTRDDVKCNIIYVSQVHPGGWVPTAALRHVYKKEYPKFLRTFTEFVKKNVK 567

  Fly   596 DKPI 599
            .||:
 Worm   568 GKPV 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	37/90 (41%)
		PH_GPBP	42..142	CDD:270100	41/102 (40%)
		START_STARD11-like	363..601	CDD:176881	99/238 (42%)
F25H2.6	NP_492762.1	PH_GPBP	9..109	CDD:270100	39/98 (40%)
		PH	11..98	CDD:278594	37/86 (43%)
		START_STARD11-like	337..573	CDD:176881	99/238 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158799
Domainoid	1	1.000	190	1.000	Domainoid score	I1939
eggNOG	1	0.900	-	-		E1_KOG1739
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4173
Inparanoid	1	1.050	294	1.000	Inparanoid score	I1674
Isobase	1	0.950	-	0.993157	Normalized mean entropy	S3799
OMA	1	1.010	-	-		QHG52378
OrthoDB	1	1.010	-	-		D408116at33208
OrthoFinder	1	1.000	-	-		FOG0006557
OrthoInspector	1	1.000	-	-		oto20219
orthoMCL	1	0.900	-	-		OOG6_106305
Panther	1	1.100	-	-	LDO	PTHR10219
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4129
SonicParanoid	1	1.000	-	-		X4792
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790