Protein Alignment cert and OSBPL1A

DIOPT Version :9

• Sequence 1: NP_001286978.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_016881019.1
• Gene: OSBPL1A / 114876
• HGNCID: 16398
• Length: 968
• Species: Homo sapiens
• Alignment Length: 625
• Identity: 122/625 - (19%)
• Similarity: 226/625 - (36%)
• Gaps: 155/625 - (24%)

  Fly    10 GASPPSSNEAAAGSQSQSDASEEEE----YLDNSI------ELRGYLSKWTNYIYGWQPRYIVLK 64
            ||.|...|:   ..|...|.::..|    .:.|.:      ...|.|.|.:.: :||:..::||:
Human   217 GADPNLKNK---NDQKPLDLAQGAEMKHILVGNKVIYKALKRYEGPLWKSSRF-FGWRLFWVVLE 277

  Fly    65 DGTLSYYKSESESDF-----GCRGAISLTKA--TIKAHES---------DELR-FDVVVNNLNNW 112
            .|.||:|:.:.::..     ||:   .||:|  |:|:.:|         |.:. |.|..|:|
Human   278 HGVLSWYRKQPDAVHNIYRQGCK---HLTQAVCTVKSTDSCLFFIKCFDDTIHGFRVPKNSL--- 336

  Fly   113 CLRAETSEDRMHWVDVLQLYKADSG---STDTTSLRRHGSTMSLQSNTISLTSGGS----LKKTQ 170
                  .:.|..|::.::.:.|.|.   |.|..:......|:|......||....|    |.:..
Human   337 ------QQSREDWLEAIEEHSAYSTHYCSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREI 395

  Fly   171 RNLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDL---GDGLKSIDFKGESITFRA 232
            .|..:.:.|.:..|::|...::.::...:|..|........|:|   .:|:::...:.|....:.
Human   396 SNFLKMIKECDMAKEMLPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNKI 460

  Fly   233 TTSGV--LTTLQHCLE-----------IIAE-------SDESWKRKLER-EIDKRRRSEDQSKKL 276
            .:..:  |.|..|.||           |::|       ||...:|.|.| |....|..|::.:.|
Human   461 LSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHL 525

  Fly   277 KDEVEKMK------------------RLSYPGPDFEEGPHS----------------TLPEDEFF 307
            .....:|.                  |.|.|.|.|.....|                |:|  ..|
Human   526 GSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMP--VIF 588

  Fly   308 DAVETGLDKIEEDMQLRFKLKLQSQISQTLVNVPHEAVAEGEEAREEFGTGAEATSHALWPEIDR 372
            :...:.|.::.|.|:..:.:...|.:|..:..:  :.||       .|...|.|:.   |....:
Human   589 NEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM--QCVA-------AFAVSAVASQ---WERTGK 641

  Fly   373 VCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEEVNGLVMDPLKAYHTVQGVTAREMCHYFF 437
            .....|          |..:::..|:...::.  .|:|:.  ..|:.|:| .:|:....:.|...
Human   642 PFNPLL----------GETYELVRDDLGFRLI--SEQVSH--HPPISAFH-AEGLNNDFIFHGSI 691

  Fly   438 MPEFRNDWETTLEDCTILEKISADTLLFLQTHKRIWPASQRDAQFWSHMRKITDNLEPGARDMWV 502
            .|:.: .|..::|    .|.....||..|:         ..:|..|::......|:..|  .:|:
Human   692 YPKLK-FWGKSVE----AEPKGTITLELLE---------HNEAYTWTNPTCCVHNIIVG--KLWI 740

  Fly   503 VCNNSTEYAKQESKNGKCVRIFLTV-ILACQTHLPEGYVK 541
            ....:.|....:: ..|||..|... :...:.|..|||::
Human   741 EQYGNVEIINHKT-GDKCVLNFKPCGLFGKELHKVEGYIQ 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	26/112 (23%)
		PH_GPBP	42..142	CDD:270100	30/119 (25%)
		START_STARD11-like	363..601	CDD:176881	32/180 (18%)
OSBPL1A	XP_016881019.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910