DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cert and Osbpl11

DIOPT Version :9

Sequence 1:	NP_001286978.1	Gene:	cert / 38928	FlyBaseID:	FBgn0027569	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_789810.2	Gene:	Osbpl11 / 106326	MGIID:	2146553	Length:	757	Species:	Mus musculus

Alignment Length:	375	Identity:	94/375 - (25%)
Similarity:	154/375 - (41%)	Gaps:	68/375 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NAGESL--GA-SPPSSNEAAAGSQSQSDASEEEEYLDNSIELRGYLSKWTNYIYGWQPRYIVLKD 65
            |:|.|.  || |..|||.:..||      ::..:|.|:...:.|||.|:||.:.|||.|:.||.:
Mouse    37 NSGNSSCGGAISSSSSNSSRGGS------AKGWQYSDHMESVNGYLMKYTNLVTGWQYRFFVLNN 95

  Fly    66 --GTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVVNNLNNWCLRAETSEDRMHWVDV 128
              |.|.|:.:|...:...||.:.|..|.|...:.|...|.|...:...:.|||..:::|.|||..
Mouse    96 EAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSR 160

  Fly   129 LQLYKADSGSTDTTSLRRHGSTMS-----LQSNTISLTSGGSLKKTQRNLREKVGELETFKDILF 188
            ||:           ..:.|...:.     |:|.:.||.|.|:...:||...:..   .:|.::..
Mouse   161 LQI-----------CTQHHTEAIGKNNPPLKSRSFSLASSGNSPISQRRPSQNA---MSFFNVGH 211

  Fly   189 GQIETLQR----YFDACSEVNK----NNAQPLDL--------GDG-LKSIDFKGESITFRATTSG 236
            .:::::.:    :.|...||.:    ...|..||        ..| |.|:|  .:.:..:||:..
Mouse   212 SKLQSVNKRAHLHPDHLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLD--QDLLMLKATSMA 274

  Fly   237 VLTTLQHCLEIIAESDESWKRK----------LEREIDKRRRSEDQSKKLKDEVEKMKRLSYPGP 291
            .:..|..|..|:.....|.::.          ||.:|......::.::: ....|..|.:..|..
Mouse   275 TMNCLNDCFHILQLQHASHQKGALPSGTTIEWLEPKIPLSNHYKNGAEQ-PFATEPNKPMGAPEA 338

  Fly   292 D--FEEGPHSTLPED-EFFDAVETGLDKIEEDM-----QLRFKLKLQSQI 333
            .  .|.|..:..||| ...|.||...|..|:|:     |....|.|.||:
Mouse   339 QCVAESGVLAREPEDINADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQL 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	31/91 (34%)
		PH_GPBP	42..142	CDD:270100	33/101 (33%)
		START_STARD11-like	363..601	CDD:176881
Osbpl11	NP_789810.2	PH_ORP10_ORP11	72..178	CDD:270106	34/116 (29%)
		PH	74..164	CDD:278594	33/100 (33%)
		Oxysterol_BP	383..743	CDD:279564	3/6 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910