Protein Alignment cert and osbpl3

DIOPT Version :9

• Sequence 1: NP_001286978.1
• Gene: cert / 38928
• FlyBaseID: FBgn0027569
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_012819861.2
• Gene: osbpl3 / 100379686
• XenbaseID: XB-GENE-950902
• Length: 912
• Species: Xenopus tropicalis
• Alignment Length: 729
• Identity: 134/729 - (18%)
• Similarity: 216/729 - (29%)
• Gaps: 273/729 - (37%)

  Fly    18 EAAAGSQSQSDASEEEEYLDNSIELRGYL---SKWTNYIYGWQPRYIVLKDGTLSYYKSESESD- 78
            |...|.:|.::..:|.|      :..|:|   .||.  :.||..||..|..|.|.|.||:::.:
 Frog    99 EIVEGLRSSTNYVQEPE------KQEGFLLKKRKWP--LKGWHKRYFFLDKGILKYSKSQADMER 155

  Fly    79 ---FGC----RGAISLTKAT--------------------------------------------- 91
               .||    ...:|:.|:|
 Frog   156 GKLHGCIDVGLSVMSVKKSTKCIDLDTEEHIYHLKVKFPEVFEEWVLKLRDHRLYRQNEISVFPH 220

  Fly    92 ---------IKAHESDELRFDVVV--------------NNLNNWCLRAET-------SEDRMHWV 126
                     |...||....||.|.              |||...||..||       |.|.|. :
 Frog   221 DLNAPFFPMISTTESASSAFDTVPSPQDFNRKNSLKLGNNLPFSCLNNETRVPAWLQSSDEME-I 284

  Fly   127 DVLQLYKADSGSTDTTSLRR-----HGSTMSLQSNTISLTSGGSLKKTQRNLREKVGELETFKDI 186
            ...:|.:..|...:.::|.:     |.:..:...|.|.:.:..|.||.:...|.|.......||.
 Frog   285 CAKELSQCHSYIVEMSNLLQNMEVLHRTYSAPSINAIQIGTIESPKKEKGIHRRKWRSKGLNKDS 349

  Fly   187 LFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTSGVLTTLQHCLEIIA-- 249
            . |.:: :...|.....::.:|       ..|.:||:..|......:.:..:|.:|..|..||
 Frog   350 K-GSLQ-VPSAFSGVMRLHASN-------PNLSTIDYAEEKQYSGGSENSEVTKMQDSLCHIANK 405

  Fly   250 -------------ESDESWKRKLEREID--------KRRRSED----QSKKLKDEVEKMKRLSYP 289
                         ...|..|:.||.:..        |...|.|    :.|.|..::....|||.
 Frog   406 AYFSLKSAYNTVFSEREKLKQFLEHDSSPSAPIAGLKNALSSDSPCEEGKTLVHQMSNESRLSI- 469

  Fly   290 GPDFEEGPHSTLPEDEFFDAVETGL------DKIEEDMQLRFKLKLQSQISQTLVNVPHEAVAEG 348
                      |....||:||.|..|      :::.:|         .|.:|....||..:.::..
 Frog   470 ----------TDSLTEFYDAQEVLLSSSSSENEVSDD---------DSYVSDISDNVSEDNLSND 515

  Fly   349 EEAREEFGTGAEATS------H--------------ALWPEIDRVCKEQLHYAREGVGQD----G 389
            .::......|...|:      |              :||           :..|..:|:|    .
 Frog   516 IDSERLSLNGGSVTTVDGCYKHRTCLLAPCPNTSNISLW-----------NILRNNIGKDLSRVS 569

  Fly   390 NGWQIFADEGEIKMYKREEEVNGLV------MDPLK--AYHTVQGVTAREMCHYF-----FMPEF 441
            ...|:......::....|.|.:.|:      .||.:  .|.....|:|.....|.     |.|..
 Frog   570 MPVQLNEPLSTLQRLCEELEYSSLLDKAAHTPDPFERMVYVATFAVSAYASSFYRAGSKPFNPVL 634

  Fly   442 RNDWETTLED---CTILEKIS-----------ADTLLFLQTHK---RIWPASQRDAQF------- 482
            ...:|...||   ..|.|::|           ::..:|.|..:   :.|..|....|.
 Frog   635 GETYEFIKEDQGFRFISEQVSHHPPISACHADSENFVFFQDMRWKNKFWGKSMEIVQIGTTHLIL 699

  Fly   483 --------WSHMRKITDNLEPGARDMWV--------------VCNNSTEYAKQE----------- 514
                    |:.:.....|:..|.|  |:              .|:....:.|.:
 Frog   700 PGFGDHYEWNKVTSCIHNILSGQR--WIEHYGEIIIKNTKSDTCHCKVTFVKAKYWNPNVHEIEG 762

  Fly   515 ---SKNGKCV-RIF 524
               .:|||.| |||
 Frog   763 TVMDRNGKVVHRIF 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	35/175 (20%)
		PH_GPBP	42..142	CDD:270100	37/185 (20%)
		START_STARD11-like	363..601	CDD:176881	43/260 (17%)
osbpl3	XP_012819861.2	PH_ORP3_ORP6_ORP7	96..216	CDD:270104	24/124 (19%)
		Oxysterol_BP	552..896	CDD:395990	42/238 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910