DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cert and plekha3

DIOPT Version :9

Sequence 1:	NP_001286978.1	Gene:	cert / 38928	FlyBaseID:	FBgn0027569	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001120200.1	Gene:	plekha3 / 100145244	XenbaseID:	XB-GENE-961095	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	269	Identity:	71/269 - (26%)
Similarity:	123/269 - (45%)	Gaps:	39/269 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVV 106
            :.|.|.||||||.|||||:.||.:|.||||.|:.:...|.:|:|.:....||.|.:|..|.::::
Frog     1 MEGVLYKWTNYITGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSTDNTRMELII 65

  Fly   107 NNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQR 171
            ....::.::|..:.:|..|:..|...||......|...:                   .:.:|..
Frog    66 PGEQHFYVKAVNAAERQRWLVALGSSKACLADNRTRKEK-------------------EISETNE 111

  Fly   172 NLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTSG 236
            :|:.|:.||..:.|:|..|:.|:|.:      ||.:..:|....:.:..     .|....||.:.
Frog   112 SLKTKMSELRLYCDLLMQQVHTIQEF------VNHDEHRPSPSTENMNE-----ASSLLSATCNT 165

  Fly   237 VLTTLQHCLEIIAESDESWKRKLEREIDKRRRSEDQSKKLKDEVEKMKR-LSYPGPDFEEGPHST 300
            .:|||:.|::|   ::..:|.::.:.:     ..|.|......|:.||| :|:||....||...:
Frog   166 FITTLEECVKI---ANAKFKPEMYQLV-----PHDVSAVSPSPVQMMKRSMSHPGTYISEGGSQS 222

  Fly   301 LPEDEFFDA 309
            ..:..|..|
Frog   223 YKDSSFHRA 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cert	NP_001286978.1	PH	40..130	CDD:278594	32/87 (37%)
		PH_GPBP	42..142	CDD:270100	35/99 (35%)
		START_STARD11-like	363..601	CDD:176881
plekha3	NP_001120200.1	PH_FAPP1_FAPP2	1..100	CDD:269951	35/98 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910